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BioWorld - Monday, April 20, 2026
Home » Topics » Drugs » Antibody

Antibody
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Elderly woman holding illustration of brain with missing puzzle piece

Meta-analysis: Anti-amyloid Alzheimer’s drugs not ‘clinically meaningful’

April 16, 2026
By Nuala Moran
No Comments
The ongoing controversy over the effectiveness of anti-amyloid drugs is about to get more heated, after a review of clinical trials showed statistically significant results do not read across to clinical benefit for patients with Alzheimer’s disease.
Read More
Amazon Bio Discovery AI-powered application
Drug design, drug delivery & technologies

More of everything as Amazon moves into AI-driven drug R&D

April 15, 2026
By Nuala Moran
No Comments
Amazon is extending the reach of its “everything store” into drug R&D with the launch of an artificial intelligence-powered Bio Discovery business. The company has compiled a catalogue of 40-plus foundation models that have been trained on extensive biology datasets and are able to generate and evaluate drug molecules in silico. For now, this covers antibodies only, but it is intended to move into other modalities.
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Open blue capsule with yellow radioactive symbol

Regeneron enters radiopharma space via Telix deal

April 14, 2026
By Tamra Sami
No Comments
Regeneron Pharmaceuticals Inc. is entering the radiopharmaceutical space via a collaboration with Telix Pharmaceuticals Ltd. to jointly develop and commercialize next-generation radiopharmaceutical therapies.
Read More
Amazon Bio Discovery AI-powered application

More of everything as Amazon moves into AI-driven drug R&D

April 14, 2026
By Nuala Moran
No Comments
Amazon is extending the reach of its “everything store” into drug R&D with the launch of an artificial intelligence-powered Bio Discovery business. The company has compiled a catalogue of 40-plus foundation models that have been trained on extensive biology datasets and are able to generate and evaluate drug molecules in silico. For now, this covers antibodies only, but it is intended to move into other modalities.
Read More
Open blue capsule with yellow radioactive symbol

Regeneron enters radiopharma space via Telix deal

April 13, 2026
By Tamra Sami
No Comments
Regeneron Pharmaceuticals Inc. is entering the radiopharmaceutical space via a collaboration with Telix Pharmaceuticals Ltd. to jointly develop and commercialize next-generation radiopharmaceutical therapies.
Read More
Illustration of knee joint, giant cell tumor of bone

Synox en route to approval on positive phase III for TGCT

April 13, 2026
By Nuala Moran
No Comments

Synox Therapeutics Ltd. is preparing to file for FDA approval of emactuzumab in treating tenosynovial giant cell tumor (TGCT), after announcing positive top-line phase III results.


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Coronavirus viral membrane
Infection

ACE2-nanobody fusion enables pan-sarbecovirus neutralization

April 13, 2026
No Comments
SARS-CoV-2 utilizes the angiotensin-converting enzyme 2 (ACE2) receptor for cell entry and triggers ACE2 ectodomain shedding, which results in elevated vasoconstrictor angiotensin II (Ang-II) while depleting the protective Ang-(1-7). This effect can lead to acute respiratory distress syndrome, hypertension, acute kidney injury and organ damage.
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T cells
Immune

Innovent presents data on IBI-3055 for autoimmune diseases

April 10, 2026
No Comments
Innovent Biologics Inc. has presented preclinical data on IBI-3055, a trispecific T-cell engager for the treatment of autoimmune diseases. This trispecific antibody targets CD19, BCMA and CD3, and features an innovative 1+1+1 T-cell engager design with CD3 masking to minimize non-specific T-cell activation.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Connecting puzzle pieces
Neurology/psychiatric

Korsana boosts Alzheimer’s work with reverse merger, $380M financing

April 2, 2026
By Jennifer Boggs
No Comments
Just over a month after emerging from stealth and disclosing a $150 million series A, Korsana Biosciences Inc. is making the leap to the public market via a merger with Cyclerion Therapeutics Inc.  The agreement, which is backed by a $370 million private placement from Korsana’s investors, solidly positions the newly merged company as it heads toward the clinic with KRSA-028, a next-generation shuttled antibody targeting amyloid beta for the treatment of Alzheimer’s disease, and builds out a pipeline of neurodegenerative disease candidates.
Read More
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