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BioWorld - Tuesday, June 30, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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Concept art of an antibody-drug conjugate
Immuno-oncology

Valanx Biotech secures funding to advance LIV-1-targeted ADC

March 12, 2026
No Comments
Valanx Biotech Gmbh has secured €3 million (US$4 million) in funding to advance its lead antibody-drug conjugate (ADC) program. The financing will enable preclinical development of VLX-ADC-001.
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Cancer

Shanghai Chempartner describes new ADCs targeting HER2 and TROP2

March 9, 2026
Shanghai Chempartner Co. Ltd. has identified antibody-drug conjugates (ADCs) comprising HER2 (erbB2) or tumor-associated calcium signal transducer 2 (TACSTD2; TROP2) covalently linked to eribulin through a linker reported to be useful for the treatment of cancer.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

March 3, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
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Antibody-drug conjugates floating on light purple background
Immuno-oncology

Next-generation dual-payload ADCs advance in oncology pipelines

March 2, 2026
No Comments
Researchers from Sutro Biopharma Inc. presented data on dual-payload antibody-drug conjugates (ADCs) engineered to overcome drug resistance, demonstrating enhanced cytotoxicity and potential efficacy in resistant cancer models.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

Feb. 27, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
Read More
3D rendering of drug linked to antibody
Cancer

Promatix EGFR×EphA2 bispecific ADC exerts antitumor activity

Feb. 27, 2026
No Comments
Researchers from Promatix Biosciences Ltd. presented preclinical data on PBS29301A, a first-in-class bispecific ADC developed using Promatix’s proprietary proteomics-based discovery platform.
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Antibody-drug conjugate illustration
Immuno-oncology

Kivu reports KIVU-305 data, gains clearance to enter clinic

Feb. 26, 2026
No Comments
Kivu Bioscience Inc. has announced receipt of Human Research Ethics Committee approval and clinical trial notification clearance in Australia to initiate a first-in-human trial of KIVU-305, its CEACAM5-targeted antibody-drug conjugate.
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Immuno-oncology

Sichuan Kelun-Biotech Biopharmaceutical discovers new ADCs targeting CDH3

Feb. 16, 2026
Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. has described antibody-drug conjugates (ADCs) comprising antibodies targeting cadherin-3 (CDH3; CDHP; P-cadherin) covalently linked to cytotoxic drug through a linker. They are reported to be useful for the treatment of cancer.
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Lab mouse

Human-relevant models lining up to replace animal tests

Feb. 12, 2026
By Nuala Moran
No Comments
The pressure to replace animal testing with human-relevant assays that are more predictive of human-drug responses has now reached a tipping point, and there is a movement toward greater acceptance of these potentially more translatable tests.
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