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BioWorld - Friday, July 31, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Dollar symbol with arrow graph

Cytomx soars as early colorectal cancer data beat expectations

March 16, 2026
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Shares of Cytomx Therapeutics Inc. hit a new 52-week high as the company unveiled preliminary data from an ongoing phase I study of varsetatug masetecan (Varseta-M) in late-line metastatic colorectal cancer. 


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Lee Byoung-chul, CEO, Kanaph

Kanaph’s $27M IPO to aid multi-modality cancer, immune portfolio

March 16, 2026
By Marian (YoonJee) Chu
No Comments
Multi-modality platform company Kanaph Therapeutics Inc. raised ₩40 billion (US$26.7 million) through its Kosdaq stock sale March 16, becoming the first Korean biotech to go public this year. The Seoul-based company’s shares (KOSDAQ:0082N0) climbed to ₩70,000 in intraday trading before closing at ₩50,600 – 153% higher than the offering price.
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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Concept art of an antibody-drug conjugate
Immuno-oncology

Valanx Biotech secures funding to advance LIV-1-targeted ADC

March 12, 2026
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Valanx Biotech Gmbh has secured €3 million (US$4 million) in funding to advance its lead antibody-drug conjugate (ADC) program. The financing will enable preclinical development of VLX-ADC-001.
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Cancer

Shanghai Chempartner describes new ADCs targeting HER2 and TROP2

March 9, 2026
Shanghai Chempartner Co. Ltd. has identified antibody-drug conjugates (ADCs) comprising HER2 (erbB2) or tumor-associated calcium signal transducer 2 (TACSTD2; TROP2) covalently linked to eribulin through a linker reported to be useful for the treatment of cancer.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

March 3, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
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Antibody-drug conjugates floating on light purple background
Immuno-oncology

Next-generation dual-payload ADCs advance in oncology pipelines

March 2, 2026
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Researchers from Sutro Biopharma Inc. presented data on dual-payload antibody-drug conjugates (ADCs) engineered to overcome drug resistance, demonstrating enhanced cytotoxicity and potential efficacy in resistant cancer models.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

Feb. 27, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
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3D rendering of drug linked to antibody
Cancer

Promatix EGFR×EphA2 bispecific ADC exerts antitumor activity

Feb. 27, 2026
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Researchers from Promatix Biosciences Ltd. presented preclinical data on PBS29301A, a first-in-class bispecific ADC developed using Promatix’s proprietary proteomics-based discovery platform.
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Antibody-drug conjugate illustration
Immuno-oncology

Kivu reports KIVU-305 data, gains clearance to enter clinic

Feb. 26, 2026
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Kivu Bioscience Inc. has announced receipt of Human Research Ethics Committee approval and clinical trial notification clearance in Australia to initiate a first-in-human trial of KIVU-305, its CEACAM5-targeted antibody-drug conjugate.
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