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BioWorld - Thursday, January 1, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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China flag and vial

Medlink, Biontech ink $1B+ multitarget ADC platform license deal

June 4, 2024
By Marian (YoonJee) Chu
China’s Medilink Therapeutics (Suzhou) Co. Ltd. and Germany’s Biontech SE signed another potential $1 billion-plus deal for novel antibody-drug conjugate (ADC) targets, building off the first ADC-based licensing deal from last year.
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ADCs lead the data charge at ASCO while AI shapes the landscape

June 4, 2024
By Lee Landenberger
While there was much talk about the vast potential of artificial intelligence (AI) during one of the world’s largest research cancer conferences, antibody-drug conjugates (ADCs) continued to grab the lion’s share of attention as Corbus Pharmaceuticals Holdings Inc. and Takeda Pharmaceutical Co. Ltd. released new and positive data.
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3D illustration demonstrating antibody-drug conjugate.
Cancer

TROP-2-targeting ADCs show antiproliferative effects in models of penile squamous cell carcinoma

June 4, 2024
Researchers from Sun Yat-sen University Cancer Center (SYSUCC) presented data from a study that aimed to assess the role of trophoblast cell-surface antigen-2 (TROP-2) in penile squamous cell carcinoma (PSCC).
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3D rendering of drug linked to antibody
Immuno-oncology

Merck KGaA advances anti-GD2 ADC toward clinic for solid tumors

June 4, 2024
Merck KGaA has announced it is advancing M-3554, a potential first-in-class anti-GD2 antibody-drug conjugate (ADC), toward the clinic. M-3554 links an exatecan payload with an anti-GD2 antibody.
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Genome & Co. shares jump 30% on $426M cancer deal with Debiopharm

June 3, 2024
By Marian (YoonJee) Chu
South Korea’s Genome & Co. Ltd. (KOSDAQ:314130) shares rose nearly 30% June 3 after it disclosed a potential ₩586.38 billion (US$426 million) licensing deal for its novel antibody-drug conjugate candidate with Switzerland’s Debiopharm International SA.
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ADCs lead the data charge at ASCO while AI shapes the landscape

June 3, 2024
By Lee Landenberger
While there was much talk about the vast potential of artificial intelligence (AI) during one of the world’s largest research cancer conferences, antibody-drug conjugates (ADCs) continued to grab the lion’s share of attention as Corbus Pharmaceuticals Holdings Inc. and Takeda Pharmaceutical Co. Ltd. released new and positive data.
Read More
Lung cancer illustration
Immuno-oncology

Almac Discovery nominates bispecific ADC for refractory lung cancer

May 31, 2024
Almac Discovery Ltd. has nominated a new preclinical candidate molecule, ALM-401, a first-in-class bispecific antibody-drug conjugate (ADC) targeting EGFR/ROR1. It is being developed for the treatment of refractory lung cancer characterized by dual expression of ROR1 and EGFR.
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China flag and vial

Medlink, Biontech ink $1B+ multitarget ADC platform license deal

May 29, 2024
By Marian (YoonJee) Chu
China’s Medilink Therapeutics (Suzhou) Co. Ltd. and Germany’s Biontech SE signed another potential $1 billion-plus deal for novel antibody-drug conjugate (ADC) targets, building off the first ADC-based licensing deal from last year.
Read More
Blood cells and destruction of cancer cell
Cancer

A pan-approach against blood cancer preserving hematopoiesis

May 29, 2024
By Mar de Miguel
A group of scientists from Basel University Hospital have designed an antibody-drug conjugate (ADC) that eliminated blood cancer cells without attacking healthy hematopoietic stem cells (HSCs), which they modified by base editing and transplanted to renew an altered blood system. They achieved this by focusing on the panhematopoietic marker CD45.
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Globe showing Asia-Pacific region

Astrazeneca in Asia: $604M Nona deal, $1.5B Singapore ADC plant

May 28, 2024
By Marian (YoonJee) Chu
Cambridge, U.K.-based Astrazeneca plc is looking to Asia, specifically China and Singapore, to build an innovative cancer-focused pipeline filled with antibody-drug conjugates (ADC), monoclonal antibodies (MAbs) and cell therapies.
Read More
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