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BioWorld - Thursday, April 2, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Immuno-oncology

Shanghai Fudan-Zhangjiang Bio-Pharmaceutical’s FZ-AD005 receives IND clearance in China

June 5, 2024
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co. Ltd. has received IND clearance in China by the National Medical Products Administration (NMPA) to conduct a phase I trial of its antibody-drug conjugate (ADC) FZ-AD005 for advanced solid tumors.
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Immuno-oncology

ACR-246 demonstrates best-in-class 5T4-targeting ADC properties in preclinical solid tumor models

June 5, 2024
Hangzhou Adcoris BioPharma Co. Ltd. is developing ACR-246, a novel 5T4-targeted antibody-drug-conjugate (ADC), for the treatment of solid tumors.
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Genome & Co. shares jump 30% on $426M cancer deal with Debiopharm

June 4, 2024
By Marian (YoonJee) Chu
South Korea’s Genome & Co. Ltd. (KOSDAQ:314130) shares rose nearly 30% June 3 after it disclosed a potential ₩586.38 billion (US$426 million) licensing deal for its novel antibody-drug conjugate candidate with Switzerland’s Debiopharm International SA.
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China flag and vial

Medlink, Biontech ink $1B+ multitarget ADC platform license deal

June 4, 2024
By Marian (YoonJee) Chu
China’s Medilink Therapeutics (Suzhou) Co. Ltd. and Germany’s Biontech SE signed another potential $1 billion-plus deal for novel antibody-drug conjugate (ADC) targets, building off the first ADC-based licensing deal from last year.
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ADCs lead the data charge at ASCO while AI shapes the landscape

June 4, 2024
By Lee Landenberger
While there was much talk about the vast potential of artificial intelligence (AI) during one of the world’s largest research cancer conferences, antibody-drug conjugates (ADCs) continued to grab the lion’s share of attention as Corbus Pharmaceuticals Holdings Inc. and Takeda Pharmaceutical Co. Ltd. released new and positive data.
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3D illustration demonstrating antibody-drug conjugate.
Cancer

TROP-2-targeting ADCs show antiproliferative effects in models of penile squamous cell carcinoma

June 4, 2024
Researchers from Sun Yat-sen University Cancer Center (SYSUCC) presented data from a study that aimed to assess the role of trophoblast cell-surface antigen-2 (TROP-2) in penile squamous cell carcinoma (PSCC).
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3D rendering of drug linked to antibody
Immuno-oncology

Merck KGaA advances anti-GD2 ADC toward clinic for solid tumors

June 4, 2024
Merck KGaA has announced it is advancing M-3554, a potential first-in-class anti-GD2 antibody-drug conjugate (ADC), toward the clinic. M-3554 links an exatecan payload with an anti-GD2 antibody.
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Genome & Co. shares jump 30% on $426M cancer deal with Debiopharm

June 3, 2024
By Marian (YoonJee) Chu
South Korea’s Genome & Co. Ltd. (KOSDAQ:314130) shares rose nearly 30% June 3 after it disclosed a potential ₩586.38 billion (US$426 million) licensing deal for its novel antibody-drug conjugate candidate with Switzerland’s Debiopharm International SA.
Read More

ADCs lead the data charge at ASCO while AI shapes the landscape

June 3, 2024
By Lee Landenberger
While there was much talk about the vast potential of artificial intelligence (AI) during one of the world’s largest research cancer conferences, antibody-drug conjugates (ADCs) continued to grab the lion’s share of attention as Corbus Pharmaceuticals Holdings Inc. and Takeda Pharmaceutical Co. Ltd. released new and positive data.
Read More
Lung cancer illustration
Immuno-oncology

Almac Discovery nominates bispecific ADC for refractory lung cancer

May 31, 2024
Almac Discovery Ltd. has nominated a new preclinical candidate molecule, ALM-401, a first-in-class bispecific antibody-drug conjugate (ADC) targeting EGFR/ROR1. It is being developed for the treatment of refractory lung cancer characterized by dual expression of ROR1 and EGFR.
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