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BioWorld - Friday, April 10, 2026
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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AI-generated image for cancer cells observed under a microscope
Immuno-oncology

Bioatla’s anti-Nectin-4 ADC gains IND clearance

May 7, 2024
Bioatla Inc. has received FDA clearance of its IND application for BA-3361, a conditionally active biologic (CAB)-Nectin-4 antibody-drug conjugate (ADC) for the treatment of multiple tumor types.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

GB01-VA-PL2202, a Claudin-6-targeting ADC with potent antitumor efficacy and bystander killing activity

May 7, 2024
Researchers from ADC Therapeutics SA presented the discovery and preclinical evaluation of a novel camptothecin-based Claudin-6-specific antibody-drug conjugate (ADC), GB01-VA-PL2202.
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Hand holding dollar sign
Cancer

Covalent proteins? Enlaza views opportunity with $100M series A

May 6, 2024
By Jennifer Boggs
“A white space opportunity.” That’s how Enlaza Therapeutics Inc. co-founder and CEO Sergio Duron described to BioWorld the company’s efforts to develop the first covalent biologics, an endeavor that has gained the backing of an impressive group of investors in a recently closed $100 million series A round.
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Grey dollar sign on grey background
Newco news

Covalent proteins? Enlaza views opportunity with $100M series A

April 30, 2024
By Jennifer Boggs
“A white space opportunity.” That’s how Enlaza Therapeutics Inc. co-founder and CEO Sergio Duron described to BioWorld the company’s efforts to develop the first covalent biologics, an endeavor that has gained the backing of an impressive group of investors in a recently closed $100 million series A round.
Read More

Full US approval for Pfizer/Genmab cervical cancer drug Tivdak

April 30, 2024
By Karen Carey
Ten days early, the U.S. FDA granted full approval under priority review to Pfizer Inc. and Genmab A/S’s antibody-drug conjugate Tivdak (tisotumab vedotin) to treat cervical cancer.
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Asia Bio Partnering panel
Asia Bio Partnering Forum 2024

Investors highlight hot therapy areas in Asia Pacific

April 30, 2024
By Tamra Sami
Antibody-drug conjugates are the hot spot for deals in Asia, but investors questioned whether oncology is really the place to be, during the Asia Bio Partnering Forum in Singapore April 24 to 25.
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Korea-US biotech Orum plans Kosdaq IPO following $100M+ BMS deal

April 30, 2024
By Marian (YoonJee) Chu
Orum Therapeutics Inc., of Boston and Daejeon, South Korea, is planning for an IPO on the Korea Exchange by the end of 2024, having passed a technology evaluation required for listing on the Kosdaq, a company spokesperson confirmed to BioWorld.
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Antibody-drug conjugate illustration
Immuno-oncology

AT-2604, an anti-ALPP/ALPPL2 ADC with efficacy and improved safety

April 30, 2024
Researchers from Axcynsis Therapeutics Pte. Ltd. presented the development and preclinical characterization of AT-2604, a novel antibody-drug conjugate (ADC) targeting the placental alkaline phosphatases, ALPP and ALPPL2.
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Asia Bio Partnering panel
Asia Bio Partnering Forum 2024

Investors highlight hot therapy areas in Asia Pacific

April 29, 2024
By Tamra Sami
Antibody-drug conjugates are the hot spot for deals in Asia, but investors questioned whether oncology is really the place to be, during the Asia Bio Partnering Forum in Singapore April 24 to 25.
Read More
Acute myeloid leukemia
Immuno-oncology

Bivictrix’s BVX-001 awarded US orphan drug designation for AML

April 18, 2024

Bivictrix Therapeutics plc’s BVX-001 has been awarded orphan drug designation by the FDA for acute myeloid leukemia (AML).


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