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BioWorld - Tuesday, January 27, 2026
Home » Topics » Drugs » Bispecific antibody

Bispecific antibody
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Hand pointing to IPOs on line graph

Hanx Bio sees stock drop 46% in $75M Hong Kong IPO debut

Dec. 30, 2025
By Tamra Sami
No Comments
Hanx Biopharmaceuticals (Wuhan) Co., Ltd. raised HK$586 million (US$75.37 million) in its IPO on the Hong Kong Securities Exchange (HKEX:3378) on Dec. 23 to advance its clinical stage immuno-oncology pipeline.
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Skin irritation on hands

J&J’s phase IIb AD bispecific washes up on Jersey shore

Dec. 29, 2025
By Randy Osborne
No Comments
The strategy of taking aim at IL-4Ra (type I and II receptors) and IL-31 by way of a bispecific antibody in atopic dermatitis (AD) has not worked out as well as Johnson & Johnson (J&J) hoped when, last May, the firm paid $1.25 billion to bring the product aboard by acquiring Yellow Jersey Therapeutics, a wholly owned subsidiary of Numab Therapeutics AG.
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Hand pointing to IPOs on line graph

Hanx Bio sees stock drop 46% in $75M Hong Kong IPO debut

Dec. 24, 2025
By Tamra Sami
No Comments
Hanx Biopharmaceuticals (Wuhan) Co., Ltd. raised HK$586 million (US$75.37 million) in its IPO on the Hong Kong Securities Exchange (HKEX:3378) on Dec. 23 to advance its clinical stage immuno-oncology pipeline.
Read More
Asia focused map inside light bulb
The year in review

Big pharma taps fast Asia innovation in search of next Keytruda

Dec. 23, 2025
By Marian (YoonJee) Chu
No Comments
Speed and innovation from Asia Pacific’s (APAC) biotechnology sector had big pharma scouring the region for the next oncology heir to Keytruda (pembrolizumab), Merck & Co. Inc.’s reigning blockbuster cancer drug.
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Immuno-oncology

Crossbow Therapeutics highlights activity of TERT-targeting CBX-663

Dec. 23, 2025
No Comments
Crossbow Therapeutics Inc. has provided details on the preclinical characterization for the telomerase reverse transcriptase (TERT)-targeting T-cell engager CBX-663.
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Illustration of T cells attacking tumor
Cancer

Disco closes €36M seed round to advance surfaceome technology

Dec. 12, 2025
By Nuala Moran
No Comments
Disco Pharmaceuticals GmbH announced the final close of its seed round at €36 million (US$42 million), as it shapes up novel targets it has discovered with its surfaceome platform technology for formal preclinical development.
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Illustration of T cells attacking tumor

Disco closes €36M seed round to advance surfaceome technology

Dec. 11, 2025
By Nuala Moran
No Comments
Disco Pharmaceuticals GmbH announced the final close of its seed round at €36 million (US$42 million), as it shapes up novel targets it has discovered with its surfaceome platform technology for formal preclinical development.
Read More
Aimedbio IPO

Aimedbio debuts with $48M Kosdaq IPO

Dec. 9, 2025
By Marian (YoonJee) Chu
No Comments
Aimedbio Inc. raised ₩70.73 billion (US$48.24 million) in its Dec. 4 IPO, marking the largest Kosdaq listing this year.
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Green and red bispecific antibodies

Crescent, Kelun in two-way deal, including PD-1/VEGF bispecific

Dec. 9, 2025
By Marian (YoonJee) Chu
No Comments
Crescent Biopharma Inc. teamed with Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. to generate “parallel” data of its PD-1/VEGF bispecific antibody, CR-001. The goal is to get 2027 readouts of the bispecific as a monotherapy and as a combination therapy with antibody-drug conjugates in both the U.S. and China.
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Multiple myeloma illustration

ASH 2025: Tec-dara shines on ‘functional cure’ Majestec-3 MM data

Dec. 9, 2025
By Karen Carey
Impressive results of a potential second-line combination treatment for multiple myeloma from the Majestec-3 trial of teclistamab plus daratumumab raised eyebrows at the American Society of Hematology’s 67th annual meeting, with the combination showing an 83.4% rate of progression-free survival at three years vs. 29.7% for standard of care.
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