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BioWorld - Monday, April 20, 2026
Home » Topics » Drugs » Bispecific antibody

Bispecific antibody
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Immuno-oncology

Crossbow Therapeutics highlights activity of TERT-targeting CBX-663

Dec. 23, 2025
No Comments
Crossbow Therapeutics Inc. has provided details on the preclinical characterization for the telomerase reverse transcriptase (TERT)-targeting T-cell engager CBX-663.
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Illustration of T cells attacking tumor
Cancer

Disco closes €36M seed round to advance surfaceome technology

Dec. 12, 2025
By Nuala Moran
No Comments
Disco Pharmaceuticals GmbH announced the final close of its seed round at €36 million (US$42 million), as it shapes up novel targets it has discovered with its surfaceome platform technology for formal preclinical development.
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Illustration of T cells attacking tumor

Disco closes €36M seed round to advance surfaceome technology

Dec. 11, 2025
By Nuala Moran
No Comments
Disco Pharmaceuticals GmbH announced the final close of its seed round at €36 million (US$42 million), as it shapes up novel targets it has discovered with its surfaceome platform technology for formal preclinical development.
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Aimedbio IPO

Aimedbio debuts with $48M Kosdaq IPO

Dec. 9, 2025
By Marian (YoonJee) Chu
No Comments
Aimedbio Inc. raised ₩70.73 billion (US$48.24 million) in its Dec. 4 IPO, marking the largest Kosdaq listing this year.
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Green and red bispecific antibodies

Crescent, Kelun in two-way deal, including PD-1/VEGF bispecific

Dec. 9, 2025
By Marian (YoonJee) Chu
No Comments
Crescent Biopharma Inc. teamed with Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. to generate “parallel” data of its PD-1/VEGF bispecific antibody, CR-001. The goal is to get 2027 readouts of the bispecific as a monotherapy and as a combination therapy with antibody-drug conjugates in both the U.S. and China.
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Multiple myeloma illustration

ASH 2025: Tec-dara shines on ‘functional cure’ Majestec-3 MM data

Dec. 9, 2025
By Karen Carey
Impressive results of a potential second-line combination treatment for multiple myeloma from the Majestec-3 trial of teclistamab plus daratumumab raised eyebrows at the American Society of Hematology’s 67th annual meeting, with the combination showing an 83.4% rate of progression-free survival at three years vs. 29.7% for standard of care.
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Green and red bispecific antibodies

Crescent, Kelun in two-way deal, including PD-1/VEGF bispecific

Dec. 5, 2025
By Marian (YoonJee) Chu
No Comments
Crescent Biopharma Inc. teamed with Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. to generate “parallel” data of its PD-1/VEGF bispecific antibody, CR-001. The goal is to get 2027 readouts of the bispecific as a monotherapy and as a combination therapy with antibody-drug conjugates in both the U.S. and China.
Read More
3D Euro symbol
Immuno-oncology

Laigo raises €11.5M seed money for targeted protein degradation

Dec. 5, 2025
By Nuala Moran
No Comments
Laigo Bio BV has raised €11.5 million (US$13.7 million) in a seed round for the further development of a new approach to inducing targeted protein degradation by E3 ubiquitin ligases.
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Cancer

CR-001, a PD-1 x VEGF bispecific antibody with potent activity

Dec. 5, 2025
No Comments
Researchers from Crescent Biopharma Inc. and Paragon Therapeutics Inc. presented the preclinical development of CR-001.
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Illustration of antibodies targeting cancer cell
Immuno-oncology

Crescent Biopharma partners with Kelun-Biotech in oncology

Dec. 5, 2025
No Comments
Crescent Biopharma Inc. has announced a new partnership with Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. and reported progress across its pipeline, with three distinct programs set to enter the clinic next year.
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