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BioWorld - Monday, May 4, 2026
Home » Topics » Drugs » Bispecific antibody

Bispecific antibody
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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Skin irritation on hands
Immune

HX-16108 holds promise for treating inflammatory skin diseases

March 11, 2026
No Comments
Atopic dermatitis (AD) is an inflammatory skin disease accompanied by pruritus, for which IL-13 and IL-31 are clinically validated targets. Earendil Labs Inc. has developed a bispecific antibody targeting both IL-13 and IL-31, HX-16108, with an extended half-life.
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Green and red bispecific antibodies
Dermatologic

China’s NMPA clears HBM-7575 to enter clinic in atopic dermatitis

March 9, 2026
No Comments
Harbour Biomed Ltd. and Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. have announced IND approval by China’s National Medical Products Administration (NMPA) for HBM-7575 (SKB-575) for the treatment of atopic dermatitis.
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3d rendering of bispecific antibodies
Immuno-oncology

CD19xγδ bispecific antibody selectively activates Vγ9Vδ2 T cells for the treatment of B-ALL

March 6, 2026
No Comments
B-cell acute lymphoblastic leukemia (B-ALL), characterized by the clonal expansion of immature lymphoblastic cells, is traditionally treated with lengthy chemotherapy followed by allogeneic stem cell transplantation (aSCT) for high-risk patients. However, patients with relapsed or refractory B-ALL still present a dismal prognosis.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

March 3, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

Feb. 27, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
Read More
Illustration of macrophage releasing cytokines
Inflammatory

Ailux characterizes ALX-001 for IMIDs

Feb. 24, 2026
No Comments
Researchers from Shanghai Ailux Biotechnology Co. Ltd. have disclosed preclinical data regarding their humanized bispecific antibody ALX-001 targeting TL1A and IL-23 for the potential treatment of immune-mediated inflammatory diseases (IMIDs).
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Bispecific antibodies with heavy chain in green and pink, light chain in blue and yellow
Immuno-oncology

First-in-class LTβR x EDB bispecific antibody overcomes checkpoint resistance

Feb. 23, 2026
No Comments
Researchers from Agni Bio Inc. reported the preclinical profile of AGB-201, a bispecific antibody designed to simultaneously target EDB and LTβR, while minimizing unwanted immune activation.
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Park Tae-yong, vice president and cofounder, Galux
Newco news

AI meets antibody design: Galux draws $29M series B for drug R&D

Feb. 10, 2026
By Marian (YoonJee) Chu
No Comments
Galux closed a ₩42 billion (US$29 million) series B round Feb. 10, led by Yuanta Investment to bring AI-driven “rational design” to the protein drug development process, already heavily influenced by human engineering. 
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Park Tae-yong, vice president and cofounder, Galux
Drug design, drug delivery & technologies

AI meets antibody design: Galux draws $29M series B for drug R&D

Feb. 10, 2026
By Marian (YoonJee) Chu
No Comments
Galux closed a ₩42 billion (US$29 million) series B round Feb. 10, led by Yuanta Investment to bring AI-driven “rational design” to the protein drug development process, already heavily influenced by human engineering.
Read More
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