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Home » Topics » Drugs » CAR T

CAR T
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Australian coins and bills

Cartherics' AU$15M series B advances CTH-401 for ovarian cancer

Oct. 2, 2024
By Tamra Sami
Immunotherapy company Cartherics Pty Ltd. raised AU$15 million (US$10.3 million) in an oversubscribed series B round that will support the first clinical trial for lead chimeric antigen receptor natural killer therapy CTH-401 for ovarian cancer, and to expand its pipeline to include other diseases.
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Fosun acquiring Fosun Kite joint venture in China for $27M

Sep. 24, 2024
By Tamra Sami
Although details are scant, Shanghai Fosun Pharmaceutical Co. Ltd. plans to buy out partner Kite Pharma Inc. (now Gilead Sciences Inc.) in the Fosun Pharma Kite Biotechnology Co. Ltd. joint venture for $27 million.
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Fosun acquiring Fosun Kite joint venture in China for $27M

Sep. 20, 2024
By Tamra Sami
Although details are scant, Shanghai Fosun Pharmaceutical Co. Ltd. plans to buy out partner Kite Pharma Inc. (now Gilead Sciences Inc.) in the Fosun Pharma Kite Biotechnology Co. Ltd. joint venture for $27 million.
Read More
Stem cells

Vor’s stem cell transplant delays cancer relapse

Sep. 6, 2024
By Lee Landenberger
Vor Biopharma Inc.’s trem-cel, a stem cell transplant designed to block the toxicity from cancer treatments, has produced some positive early stage results, including delayed relapse in patients. Phase I/IIa study data showed participants with relapsed/refractory acute myeloid leukemia benefited from trem-cel followed by treatment with Pfizer Inc.’s antibody-drug conjugate cancer fighter Mylotarg (gemtuzumab ozogamicin).
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3D rendering of CAR T therapy in cell

New Spinoza on CAR Ts: Cartesian, others pursue autoimmune

Aug. 26, 2024
By Randy Osborne
Headlines in March about Cartesian Therapeutics Inc. reminded investors of the firm’s already-intriguing push with Descartes-08, an autologous anti-BCMA mRNA CAR T therapy, in the works for myasthenia gravis and systemic lupus erythematosus. Excitement generally is mounting around prospects for CAR T therapies in autoimmune disease, where developers aplenty are pursuing early stage opportunities.
Read More
Cancer cell, dropper, test tubes

First in a decade: FDA clears Adaptimmune T-cell therapy Tecelra

Aug. 2, 2024
By Lee Landenberger
A T-cell therapy from Adaptimmune Therapeutics plc has received accelerated approval from the U.S. FDA to treat advanced synovial sarcoma (SS). Tecelra (afamitresgene autoleucel), a CAR T targeting MAGE-A4, is the first engineered T-cell therapy for solid tumors and the first treatment option for the indication in more than a decade.
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Single strand RNA

BIX Korea 2024: Promise of mRNA technology for cell and gene therapy

July 16, 2024
By Marian (YoonJee) Chu
The industry is looking, with renewed hope, to the “promise” of messenger RNA (mRNA) therapeutics for a wide range of diseases beyond COVID-19, and not only in vaccine form but also for gene and cell therapies.
Read More
Rahul Purwar, founder and CEO, Immunoact
Newco news

Immunoact lays groundwork for India cell, gene therapy innovation

July 16, 2024
By Tamra Sami
India’s first indigenous CAR T therapy is selling at around $50,000 per shot, nearly one-tenth of the price of top-selling CAR Ts in the U.S., and Immunoact founder and CEO Rahul Purwar told BioWorld he anticipates bringing the price down to as low as $20,000 per shot.
Read More
Single strand RNA

BIX Korea 2024: Promise of mRNA technology for cell and gene therapy

July 10, 2024
By Marian (YoonJee) Chu
The industry is looking, with renewed hope, to the “promise” of messenger RNA (mRNA) therapeutics for a wide range of diseases beyond COVID-19, and not only in vaccine form but also for gene and cell therapies.
Read More

Cartesian hits primary endpoint in MG phase IIb but stock wilts

July 2, 2024
By Lee Landenberger
Cartesian Therapeutics Inc.’s phase IIb study of its lead candidate, Descartes-08, in treating generalized myasthenia gravis (gMG) hit its primary endpoint while the company also notched a $130 million private placement equity financing.
Read More
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