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Home » Topics » Drugs » CAR T

CAR T
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3D rendering of CAR T therapy in cell

By the numbers: US leads charge of cell and gene therapies

Oct. 22, 2024
By Marian (YoonJee) Chu
U.S. biotechs and regulators ushered in the era of gene therapy in 2023, experts at Bio Japan said, but medical reform is needed to pave the way for the “year of cell therapy” in 2024 and implement wider access to ultra-expensive cell and gene therapies.
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3D rendering of CAR T therapy in cell

By the numbers: US leads charge of cell and gene therapies

Oct. 18, 2024
By Marian (YoonJee) Chu
U.S. biotechs and regulators ushered in the era of gene therapy in 2023, experts at Bio Japan said, but medical reform is needed to pave the way for the “year of cell therapy” in 2024 and implement wider access to ultra-expensive cell and gene therapies.
Read More
Australian coins and bills

Cartherics' AU$15M series B advances CTH-401 for ovarian cancer

Oct. 8, 2024
By Tamra Sami
Immunotherapy company Cartherics Pty Ltd. raised AU$15 million (US$10.3 million) in an oversubscribed series B round that will support the first clinical trial for lead chimeric antigen receptor natural killer therapy CTH-401 for ovarian cancer, and to expand its pipeline to include other diseases.
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Australian coins and bills
Cancer

Cartherics' AU$15M series B advances CTH-401 for ovarian cancer

Oct. 3, 2024
By Tamra Sami
Immunotherapy company Cartherics Pty Ltd. raised AU$15 million (US$10.3 million) in an oversubscribed series B round that will support the first clinical trial for lead chimeric antigen receptor natural killer therapy CTH-401 for ovarian cancer, and to expand its pipeline to include other diseases. Cartherics CEO Alan Trounson told BioWorld that the funds raised will take Cartherics through to mid-2026, and the phase I Australian trial in ovarian cancer will begin in the fourth quarter of 2025.
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Australian coins and bills

Cartherics' AU$15M series B advances CTH-401 for ovarian cancer

Oct. 2, 2024
By Tamra Sami
Immunotherapy company Cartherics Pty Ltd. raised AU$15 million (US$10.3 million) in an oversubscribed series B round that will support the first clinical trial for lead chimeric antigen receptor natural killer therapy CTH-401 for ovarian cancer, and to expand its pipeline to include other diseases.
Read More

Fosun acquiring Fosun Kite joint venture in China for $27M

Sep. 24, 2024
By Tamra Sami
Although details are scant, Shanghai Fosun Pharmaceutical Co. Ltd. plans to buy out partner Kite Pharma Inc. (now Gilead Sciences Inc.) in the Fosun Pharma Kite Biotechnology Co. Ltd. joint venture for $27 million.
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Fosun acquiring Fosun Kite joint venture in China for $27M

Sep. 20, 2024
By Tamra Sami
Although details are scant, Shanghai Fosun Pharmaceutical Co. Ltd. plans to buy out partner Kite Pharma Inc. (now Gilead Sciences Inc.) in the Fosun Pharma Kite Biotechnology Co. Ltd. joint venture for $27 million.
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Stem cells

Vor’s stem cell transplant delays cancer relapse

Sep. 6, 2024
By Lee Landenberger
Vor Biopharma Inc.’s trem-cel, a stem cell transplant designed to block the toxicity from cancer treatments, has produced some positive early stage results, including delayed relapse in patients. Phase I/IIa study data showed participants with relapsed/refractory acute myeloid leukemia benefited from trem-cel followed by treatment with Pfizer Inc.’s antibody-drug conjugate cancer fighter Mylotarg (gemtuzumab ozogamicin).
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3D rendering of CAR T therapy in cell

New Spinoza on CAR Ts: Cartesian, others pursue autoimmune

Aug. 26, 2024
By Randy Osborne
Headlines in March about Cartesian Therapeutics Inc. reminded investors of the firm’s already-intriguing push with Descartes-08, an autologous anti-BCMA mRNA CAR T therapy, in the works for myasthenia gravis and systemic lupus erythematosus. Excitement generally is mounting around prospects for CAR T therapies in autoimmune disease, where developers aplenty are pursuing early stage opportunities.
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Cancer cell, dropper, test tubes

First in a decade: FDA clears Adaptimmune T-cell therapy Tecelra

Aug. 2, 2024
By Lee Landenberger
A T-cell therapy from Adaptimmune Therapeutics plc has received accelerated approval from the U.S. FDA to treat advanced synovial sarcoma (SS). Tecelra (afamitresgene autoleucel), a CAR T targeting MAGE-A4, is the first engineered T-cell therapy for solid tumors and the first treatment option for the indication in more than a decade.
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