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BioWorld - Thursday, April 16, 2026
Home » Topics » Drugs » Immuno-oncology

Immuno-oncology
Immuno-oncology RSS Feed RSS

Lung cancer illustration
Immuno-oncology

Nanobody against CD155 to treat lung cancer

July 18, 2025
No Comments
Lung cancer is the most frequent cause of cancer-related death in both men and women worldwide. Current treatments can fail because of variable responses in different types of patients, drug resistance, poor tumor penetration and systemic toxicity, prompting the continuing search for better therapeutics.
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Immuno-oncology

Genome Therapeutics divulges new compounds and their immunoconjugates

July 10, 2025
Genome Therapeutics Ltd. has synthesized compounds and their immunoconjugates comprising an antibody covalently linked to a cytotoxic drug through a linker reported to be useful for the treatment of cancer.
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AI-generated illustration of CAR T cells
Immuno-oncology

Researchers arm CAR T cells to fight solid tumors

July 8, 2025
By Tamra Sami
No Comments
Aussie researchers have used CRISPR gene editing tools to “armor” chimeric antigen receptor (CAR) T cells to activate additional cancer-fighting proteins at the tumor site, enabling them to target cancer cells in solid tumors.
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3D pancreas illustration
Immuno-oncology

New anti-CTGF/PD-1 bispecific antibody outperforms combination therapy in remodeling PDAC microenvironment

July 7, 2025
No Comments
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, primarily due to its dense, desmoplastic and immunosuppressive tumor microenvironment (TME) that hinders the efficacy of immune checkpoint inhibitors such as anti-programmed cell death 1 (PD-1).
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3D rendering of an antibody drug conjugate
Immuno-oncology

Innocare’s ICP-B794 gains IND clearance in China

July 4, 2025
No Comments
Innocare Pharma Ltd. has obtained IND approval from China’s National Medical Products Administration (NMPA) to initiate a clinical trial of the B7-H3 targeted antibody-drug conjugate.
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Multiple myeloma illustration
Immuno-oncology

Brightpath’s BP-2202 designated orphan drug for multiple myeloma

July 4, 2025
No Comments
Brightpath Biotherapeutics Co. Ltd.’s iPS cell-derived BCMA CAR-natural killer T cell therapy candidate has been awarded orphan drug designation by the FDA for the treatment of multiple myeloma.
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Brain tumor illustration
Immuno-oncology

IL-24S/IL-15 fusion ‘superkine’ induces apoptosis of GBM cells, promotes antitumor immunity

July 4, 2025
No Comments
A recent study published in the Journal for Immunotherapy of Cancer has revealed a promising new approach for the treatment of glioblastoma (GBM), an aggressive and incurable form of primary brain cancer.
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Concept art for "cancer cells destroyed by oncogenic virus"
Immuno-oncology

IL-12-expressing oncolytic virus shows promise for solid tumors

July 3, 2025
No Comments
A newly developed oncolytic virus, SKV-012, has demonstrated promising results in preclinical studies and a phase I clinical trial for the treatment of advanced solid tumors.
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Cancer research illustration
Immuno-oncology

Boehringer Ingelheim selects new oncology drug candidate from Oxford Biotherapeutics collaboration

July 3, 2025
No Comments
Boehringer Ingelheim Pharma GmbH & Co KG has selected a third oncology drug candidate to advance into IND-enabling studies under its ongoing collaboration with Oxford Biotherapeutics Ltd.
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AI-generated illustration of CAR T cells
Immuno-oncology

Researchers arm CAR T cells to fight solid tumors

July 3, 2025
By Tamra Sami
No Comments
Aussie researchers have used CRISPR gene editing tools to “armor” chimeric antigen receptor (CAR) T cells to activate additional cancer-fighting proteins at the tumor site, enabling them to target cancer cells in solid tumors.
Read More
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