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BioWorld - Saturday, June 6, 2026
Home » Topics » Drugs » Small molecule

Small molecule
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Imcivree

Post-Emanate, Rhythm’s next Imcivree news aHO lot better?

March 17, 2026
By Randy Osborne
No Comments
Low expectations for Rhythm Pharmaceuticals Inc.’s phase III study dubbed Emanate with Imcivree (setmelanotide) in a handful of rare genetic obesities meant hardly any share price consequence, and the stock (NASDAQ:RYTM) closed March 17 at $87.68, down $2.83. “We’re not going to file [for approval] on any of these,” CEO David Meeker said, but the latest findings together represent “a solid building block going forward,” he added.
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Molecule illustration

Otsuka’s repinatrabit shows phase II efficacy in PKU adolescents

March 17, 2026
By Marian (YoonJee) Chu
No Comments
Otsuka Pharmaceutical Co. Ltd. reaped positive results from an open-label phase II study of repinatrabit (JNT-517) in adolescents with phenylketonuria (PKU), a rare disease marked by the inability to break down the amino acid phenylalanine.
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Lee Byoung-chul, CEO, Kanaph

Kanaph’s $27M IPO to aid multi-modality cancer, immune portfolio

March 17, 2026
By Marian (YoonJee) Chu
No Comments
Multi-modality platform company Kanaph Therapeutics Inc. raised ₩40 billion (US$26.7 million) through its Kosdaq stock sale March 16, becoming the first Korean biotech to go public this year. The Seoul-based company’s shares (KOSDAQ:0082N0) climbed to ₩70,000 in intraday trading before closing at ₩50,600 – 153% higher than the offering price.
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 17, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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doctor, checklist, apple, prescription bottle and blood glucose meter illustration

Hightide wins China NDA acceptance for oral metabolic therapy

March 17, 2026
By Tamra Sami
No Comments
China’s National Medical Products Administration (NMPA) has accepted for review Hightide Therapeutics Inc.’s NDA for HTD-1801 for type 2 diabetes, marking the Shenzhen-based company’s first NDA submission and a major step toward commercialization.
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Kidneys
Newco news

R1’s $77.5M series A to fund CKD trial of oral phosphate inhibitor

March 17, 2026
By Nuala Moran
No Comments
Newco R1 Therapeutics Inc. has launched with an oversubscribed $77.5 million series A, providing the means to take AP-306, a potentially first-in-class hyperphosphatemia therapy through phase IIb development in patients with chronic kidney disease.
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Lee Byoung-chul, CEO, Kanaph

Kanaph’s $27M IPO to aid multi-modality cancer, immune portfolio

March 16, 2026
By Marian (YoonJee) Chu
No Comments
Multi-modality platform company Kanaph Therapeutics Inc. raised ₩40 billion (US$26.7 million) through its Kosdaq stock sale March 16, becoming the first Korean biotech to go public this year. The Seoul-based company’s shares (KOSDAQ:0082N0) climbed to ₩70,000 in intraday trading before closing at ₩50,600 – 153% higher than the offering price.
Read More
Molecule illustration

Otsuka’s repinatrabit shows phase II efficacy in PKU adolescents

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Otsuka Pharmaceutical Co. Ltd. reaped positive results from an open-label phase II study of repinatrabit (JNT-517) in adolescents with phenylketonuria (PKU), a rare disease marked by the inability to break down the amino acid phenylalanine.
Read More
Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
Read More
Pregnancy
Immune

Uterus transplants show how immune cells shape pregnancy outcomes

March 12, 2026
By Nuala Moran
No Comments
A study involving a small cohort of women who have received womb transplants has cast fresh light on how the immune system shapes pregnancy outcomes, opening up new avenues of research into implantation failure, preeclampsia and preterm birth. Using an array of single cell analyses, scientists at the University of Alabama at Birmingham (UAB) studied the composition and gene expression profiles of immune cells in tissue samples from five women who had received womb transplants.
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