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BioWorld - Friday, February 20, 2026
Home » Topics » Drugs » Small molecule

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Elderly woman holding illustration of brain with missing puzzle piece
Neurology/psychiatric

Mair Therapeutics and Radboud collaborate in Parkinson’s

Jan. 27, 2026
No Comments
Mair Therapeutics BV has established a scientific collaboration with Radboud University to accelerate the discovery of small-molecule agonists of TMEM175, a lysosomal ion channel genetically linked to Parkinson’s disease.
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Tanabe’s dersimelagon hits phase III endpoint in rare disorder

Jan. 27, 2026
By Marian (YoonJee) Chu
No Comments
After selling off amyotrophic lateral sclerosis therapeutics last month, Tanabe Pharma America Inc. emerged a forerunner in another rare disease space with positive top-line phase III data of dersimelagon (MT-7117) for erythropoietic protoporphyria/X-linked protoporphyria.
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Asia roundup: Shionogi ups Viiv stake, Fosun spinoff plans, more

Jan. 27, 2026
By Marian (YoonJee) Chu
No Comments
Shionogi & Co. Ltd. and Fosun Pharmaceutical (Group) Co. Ltd. were involved in separate divestment transactions this week, with Shionogi buying out Pfizer Inc.’s stake in Viiv Healthcare Ltd. to lift its holding to 21.7%.
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Corxel raises $287M series D round to advance oral GLP-1

Jan. 27, 2026
By Tamra Sami
No Comments
Corxel Pharmaceuticals Ltd. completed a $287 million series D round to advance its lead compound, an oral small-molecule GLP-1 receptor agonist, CX-11, for obese and overweight patients.
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1st Biotherapeutics closes $22M series D, preps for IPO

Jan. 27, 2026
By Marian (YoonJee) Chu
No Comments
1st Biotherapeutics Inc. announced the closing of a ₩31.7 billion series D funding round Jan. 26 to advance its lead phase I oncology asset, FB-849, and portfolio of candidates for neurodegenerative diseases.
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Korean Won currency symbol made of gray cast iron

1st Biotherapeutics closes $22M series D, preps for IPO

Jan. 26, 2026
By Marian (YoonJee) Chu
No Comments
1st Biotherapeutics Inc. announced the closing of a ₩31.7 billion series D funding round Jan. 26 to advance its lead phase I oncology asset, FB-849, and portfolio of candidates for neurodegenerative diseases.
Read More
Global handshake silhouette

Asia roundup: Shionogi ups Viiv stake, Fosun spinoff plans, more

Jan. 23, 2026
By Marian (YoonJee) Chu
No Comments
Shionogi & Co. Ltd. and Fosun Pharmaceutical (Group) Co. Ltd. were involved in separate divestment transactions this week, with Shionogi buying out Pfizer Inc.’s stake in Viiv Healthcare Ltd. to lift its holding to 21.7%.
Read More
White tablet imprinted with dollar sign

Corxel raises $287M series D round to advance oral GLP-1

Jan. 23, 2026
By Tamra Sami
No Comments
Corxel Pharmaceuticals Ltd. completed a $287 million series D round to advance its lead compound, an oral small-molecule GLP-1 receptor agonist, CX-11, for obese and overweight patients.
Read More
Immune

Researchers develop 3,3-dimethyl-2-oxoindiline STING inhibitors

Jan. 23, 2026
No Comments
Hyperactivity of the transmembrane adaptor protein STING, which normally helps the cell respond to infection and injury, has been implicated in several autoimmune or inflammatory diseases, including systemic lupus erythematosus and amyotrophic lateral sclerosis.
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Foot pain illustration

Lexicon rebounds on FDA nod for phase III non-opioid pain drug trial

Jan. 22, 2026
By Marian (YoonJee) Chu
No Comments
Lexicon Pharmaceuticals Inc. announced that it received no objections from the U.S. FDA to move pilavapadin, its non-opioid candidate for diabetic peripheral neuropathic pain, into phase III study, pushing company shares up near 20% on the day.
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