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BioWorld - Wednesday, February 11, 2026
Home » Topics » Regulatory » Patents

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Cardiovascular

Bristol Myers Squibb patents new RXFP1 inhibitors

July 19, 2023
Several patents from Bristol Myers Squibb Co. describe relaxin receptor 1 (RXFP1; LGR7) agonists reported to be useful for the treatment of heart failure and fibrosis.
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Cancer

PD-1/PD-L1 interaction inhibitors described in Shanghai Maxinovel Pharmaceuticals patent

July 19, 2023
Shanghai Maxinovel Pharmaceuticals Co. Ltd. has reported the identification of programmed cell death 1 (PD-1; PDCD1; CD279)/PD-1 ligand 1 (PD-L1; CD274) interaction inhibitors reported to be useful for the treatment of cancer.
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Infection

Bioversys discovers rifabutin analogues for treatment of bacterial infections

July 19, 2023
Bioversys AG has patented new rifabutin analogues reported to be useful for the treatment of bacterial infections.
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Neurology/Psychiatric

Shanghai Institute of Materia Medica patent describes new RIPK1 inhibitors

July 18, 2023
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences have developed nitrogenous heterocyclic compounds described as as receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors.
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Cancer

Humanwell Healthcare patents TEAD inhibitors for cancer

July 18, 2023
Humanwell Healthcare (Group) Co. Ltd. has patented transcriptional enhancer factor (TEAD)...
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Cancer

Innovstone Therapeutics divulges new ENPP1 inhibitors

July 17, 2023
Innovstone Therapeutics Ltd. has described aromatic heterocyclic compounds acting as ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) inhibitors potentially useful for the treatment of pancreatic cancer, heart failure and myocardial infarction.
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Infection

Pharmablock Sciences patents Mpro inhibitors for treatment of viral infections

July 17, 2023
Research at Pharmablock Sciences (Nanjing) Inc. has led to the development of spirooxindole compounds acting as 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors and thus reported to be useful for the treatment of viral infections.
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Respiratory

Rho kinase inhibitors described in Chiesi Farmaceutici patent

July 17, 2023
Chiesi Farmaceutici SpA has identified dihydrofuropyridine derivatives acting as Rho kinase 1 (ROCK1; p160-ROCK) and/or Rho kinase 2 (ROCK2; ROCKα) inhibitors.
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Dermatologic

Almirall prepares and tests heterobicyclic EMT inhibitors

July 17, 2023
Heterobicyclic derivatives characterized as tyrosine-protein kinase ITK/TSK (EMT) inhibitors have been revealed in an Almirall SA patent. They are reported to be useful for the treatment of atopic dermatitis, psoriasis, T-cell lymphoma, alopecia areata and vitiligo.
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Dermatologic

Leo Pharma patent details new IL-17 modulators

July 17, 2023
Leo Pharma A/S has patented new interleukin-17 (IL-17) modulators reported to be useful for the treatment of psoriasis and more.
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