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BioWorld - Thursday, July 9, 2026
Home » Topics » Asia-Pacific » Japan

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Xray showing lung cancer on tablet

Astrazeneca, Daiichi won’t cop to TROP2 grade 5s; OS data from phase III yet to emerge

July 11, 2023
By Randy Osborne
The trophoblast cell surface antigen 2 (TROP2) class chalked mix news by way of Astrazeneca plc and Daiichi Sankyo Co. Ltd. as the pair disclosed phase III data from the closely watched Tropion-Lung 1 trial with datopotamab deruxtecan (dato-dxd) against non-small-cell lung cancer.
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Xray showing lung cancer on tablet

Astrazeneca, Daiichi won’t cop to TROP2 grade 5s; OS data from phase III yet to emerge

July 3, 2023
By Randy Osborne
The trophoblast cell surface antigen 2 (TROP2) class chalked mix news by way of Astrazeneca plc and Daiichi Sankyo Co. Ltd. as the pair disclosed phase III data from the closely watched Tropion-Lung 1 trial with datopotamab deruxtecan (dato-dxd) against non-small-cell lung cancer.
Read More
Illustration of cancer in the bile ducts

Japan’s MHLW gives nod to Taiho’s FGFR inhibitor Lytgobi for biliary tract cancer

June 27, 2023
By Tamra Sami
Japan’s Ministry of Health, Labour and Welfare approved Taiho Pharmaceutical Co. Ltd.’s Lytgobi (futibatinib) for unresectable biliary tract cancer harboring fibroblast growth factor receptor 2 (FGFR2) gene fusions that has progressed after chemotherapy.
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Healios, Sumitomo begin phase I/II trial of allogeneic iPS cells in retinal pigment epithelium tears

June 27, 2023
By Tamra Sami
Japan’s Pharmaceutical and Medical Devices Agency has cleared Healios K.K. and Sumitomo Pharma Co. Ltd. to begin a phase I/II study of HLCR-011, which is composed of retinal pigment epithelial (RPE) cells derived from allogeneic induced pluripotent stem cells (iPS) in patients with RPE tear.
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Digital handshake

Aslan signs $138.5M licensing deal with Zenyaku for atopic dermatitis drug eblasakimab in Japan

June 27, 2023
By Marian (YoonJee) Chu
Aslan Pharmaceuticals Pte Ltd. said it inked a licensing deal with Zenyaku Kogyo Co. Ltd. for its atopic dermatitis-targeting monoclonal antibody, eblasakimab, that could reach $138.5 million in up-front and milestone payments.
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Shionogi to acquire Qpex for $140M to expand antimicrobial pipeline

June 27, 2023
By Tamra Sami
Shionogi & Co. Ltd.’s U.S. subsidiary Shinogi Inc. will acquire San Diego-based Qpex Biopharma Inc. in a deal worth up to $140 million that expands Shionogi’s pipeline of infectious disease agents and also adds to Brii Biosciences Ltd.’s pipeline.
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Shionogi to acquire Qpex for $140M to expand antimicrobial pipeline

June 26, 2023
By Tamra Sami
Shionogi & Co. Ltd.’s U.S. subsidiary Shinogi Inc. will acquire San Diego-based Qpex Biopharma Inc. in a deal worth up to $140 million that expands Shionogi’s pipeline of infectious disease agents and also adds to Brii Biosciences Ltd.’s pipeline.
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Healios, Sumitomo begin phase I/II trial of allogeneic iPS cells in retinal pigment epithelium tears

June 23, 2023
By Tamra Sami
Japan’s Pharmaceutical and Medical Devices Agency has cleared Healios K.K. and Sumitomo Pharma Co. Ltd. to begin a phase I/II study of HLCR-011, which is composed of retinal pigment epithelial (RPE) cells derived from allogeneic induced pluripotent stem cells (iPS) in patients with RPE tear.
Read More
Digital handshake

Aslan signs $138.5M licensing deal with Zenyaku for atopic dermatitis drug eblasakimab in Japan

June 23, 2023
By Marian (YoonJee) Chu
Aslan Pharmaceuticals Pte Ltd. said it inked a licensing deal with Zenyaku Kogyo Co. Ltd. for its atopic dermatitis-targeting monoclonal antibody, eblasakimab, that could reach $138.5 million in up-front and milestone payments.
Read More
Global handshake silhouette

Astellas and Cullgen join forces on potential $1.9B protein degraders pact

June 20, 2023
By Caroline Richards
Astellas Pharma Inc. has agreed to pay Cullgen Inc. up to $1.9 billion-plus to jointly develop multiple protein degraders. Under the agreement, Tokyo-based Astellas will pay Cullgen, of San Diego, $35 million up front, and an additional $85 million if it decides, during the initial stages of development, to jointly commercialize and promote Cullgen’s lead program, a cell cycle protein degrader for the treatment of breast cancer and other solid tumors, in the U.S.
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