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BioWorld - Thursday, May 7, 2026
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BioWorld Science, Infection
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Infection

Ciprofloxacin prodrug effectively disrupts biofilm formation

April 29, 2025
Researchers from Foshan University described a ciprofloxacin prodrug designed to treat biofilm-associated drug-resistant P. aeruginosa infections.
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Virus and drug illustration
Infection

GS-1 prevents varicella-zoster and herpes simplex virus entry

April 25, 2025
Varicella-zoster virus (VZV) causes chickenpox and shingles, while herpes simplex virus (HSV) is responsible for oral and genital herpes. Although current treatments mainly focus on inhibiting viral replication, there is a critical need for new therapies to address the limitations and side effects associated with existing treatments.
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Gavel and scales
Policy

Harvard fighting back with lawsuit against Trump administration

April 23, 2025
By Nuala Moran
Harvard University has filed a lawsuit claiming the Trump administration’s freezing of its federal funding is unlawful and beyond the government’s authority. Announcing the move, Harvard’s president, Alan Garber, highlighted the impact of freezing $2.2 billion in grants – and the threat to freeze a further $1.1 billion – will have on the university’s biomedical research.
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Infection

Crestone’s CRS-700159 shows antiviral activity against coronaviruses

April 23, 2025
Crestone Inc. has presented data regarding their viral protease inhibitor proteolysis targeting chimera PROTAC CRS-700159.
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Antibodies and red blood cells
Infection

USAMRIID and Lifearc collaborate on mAb Crimean-Congo hemorrhagic fever virus

April 23, 2025
The U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) and medical research charity Lifearc have announced a collaboration to develop an affordable and accessible monoclonal antibody (mAb) therapeutic for Crimean-Congo hemorrhagic fever virus (CCHFV).
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Gloved hand holding petri dish containing world map
Immune

WHO member states outline pandemic plan

April 17, 2025
By Lee Landenberger
After more than three years of discussion, the World Health Organization’s Intergovernmental Negotiating Body (INB) has agreed on a proposal to prevent, prepare and respond to a pandemic. The plan is born, the INB proposal said, out of inequities around the world that slowed timely and equitable access to health products to respond to the COVID-19 pandemic.
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Infection

Humanwell Healthcare describes new cyclopeptides to treat Acinetobacter infections

April 17, 2025
Humanwell Healthcare (Group) Co. Ltd. has identified cyclopeptides reported to be useful for the treatment of Acinetobacter infections, particularly A. baumannii infections.
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Scientist with vial
Infection

Preclinical data on new composite peptide vaccine from Longhorn

April 16, 2025
At the recent European Society of Clinical Microbiology and Infectious Diseases (ESCMID) meeting in Vienna, Longhorn Vaccines & Diagnostics LLC presented data on the neutralizing antibody responses of LHNVD-202, an unconjugated composite peptide vaccine.
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Infection

Mandimycin, a polyene macrolide with potent antifungal activity and distinctive mode of action

April 15, 2025
Writing in Nature, researchers from China Pharmaceutical University and Shandong University have revealed the discovery of a new polyene antifungal antibiotic, mandimycin.
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Infection

Coronavirus entry inhibitors disclosed in Yeda Research and Development patent

April 14, 2025
Yeda Research and Development Co. Ltd. has divulged broad-spectrum coronavirus entry inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19), SARS-CoV infection and Middle East respiratory syndrome coronavirus (MERS-CoV) infection.
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