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BioWorld - Thursday, July 2, 2026
Breaking News: Science fiction realized: BCI tech is hereBreaking News: Science fiction realized: BCI tech is hereBreaking News: Science fiction realized: BCI tech is here
Home » Topics » BioWorld Science, Neurology/psychiatric

BioWorld Science, Neurology/psychiatric
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Parkinson's disease illustration showing neurons containing alpha-synuclein
Neurology/Psychiatric

Stem Pharm and Verge Genomics collaborate on disease model to validate Parkinson’s targets

Oct. 11, 2023
Stem Pharm Inc. and Verge Genomics (Verge Analytics Inc.) have established a collaboration to develop a disease model to validate novel targets identified by Verge for Parkinson’s disease.
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Neurology/Psychiatric

Novel 15-PGDH inhibitor improves muscle force in models of SMA and muscle atrophy

Oct. 11, 2023
It has been previously demonstrated that therapeutic inhibition of the prostaglandin E2 (PGE2)-degrading enzyme, 15-prostaglandin dehydrogenase (15-PGDH), was able to improve muscle strength in aged mice. Researchers from Epirium Bio Inc. have now reported the discovery and preclinical characterization an orally bioavailable small molecule inhibitor of 15-PGDH – MF-300 – being developed for the treatment of neuromuscular dysfunction.
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Neurology/Psychiatric

CaMK2A modulators reported in University of California Oakland and University of Copenhagen patent

Oct. 10, 2023
University of California Oakland and University of Copenhagen scientists have jointly developed calcium/calmodulin-dependent protein kinase type II subunit α (CaMK2A) modulators reported to be useful for the treatment of brain injury, narcolepsy, Angelman syndrome, Down syndrome and stroke.
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Neurology/Psychiatric

Sosei and Pharmenable expand drug discovery collaboration to include second neurology target

Oct. 10, 2023
Sosei Group Corp. and Pharmenable Therapeutics Ltd. have expanded their collaboration to apply their respective technologies to drive novel drug discovery for a second neurological disease target.
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Neurology/Psychiatric

Curasen receives investment to advance α1A-AR agonist for Alzheimer’s disease

Oct. 10, 2023
Curasen Therapeutics Inc. has received a strategic investment of up to $5.8 million from the Alzheimer’s Drug Discovery Foundation (ADDF) to advance CST-3056, an α1A-adrenoceptor (α1A-AR) agonist for the treatment of Alzheimer’s disease.
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Biomarkers

Cathepsin C and PDGFR-α as novel biomarkers of prevalent distal sensorimotor polyneuropathy

Oct. 10, 2023
Researchers from Heinrich-Heine-Universität Düsseldorf and affiliated organizations presented data from a study that aimed to identify novel neurological biomarkers in distal sensorimotor polyneuropathy (DSPN).
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AI generated illustration of a brain on fire
Neurology/Psychiatric

ECNP 2023: Look for antibodies in idiopathic psychoses? First, maybe better tests

Oct. 10, 2023
By Anette Breindl
For individuals who develop an unexpected psychosis, there is something to be said for testing them for autoimmune antibodies. And something against. At the 36th Congress of the European College of Neuropsychopharmacology (ECNP) this week, the topic was worth a controversy session, where speakers presented the pros and cons of the approach. Currently used tests have a specificity of 99%. But as Ester Coutinho, consultant neurologist at the University of Coimbra, pointed out, the validity of diagnostic tests depends on the prevalence of the disorder one is looking for as well. Coutinho estimated that autoimmune psychoses account for 1% of psychoses overall.
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Neurology/Psychiatric

Shanghai Institute of Materia Medica patent describes Nav1.8 blockers

Oct. 9, 2023
Amide compounds acting as sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for the treatment of pain, arthritis, pruritus, asthma, multiple sclerosis, arrhythmia, heart failure and epilepsy, among others.
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Neurology/Psychiatric

Intra-Cellular Therapies patents SERT, 5-HT2A and dopamine receptor ligands

Oct. 9, 2023
Intra-Cellular Therapies Inc. has patented compounds acting as serotonin transporter (SERT), 5-HT2A, dopamine D1 and D2 receptor ligands reported to be useful for the treatment of neurological disorders.
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3D cross-section illustration of muscle anatomy
Neurology/Psychiatric

RKER-065 improves muscle function and prevents bone loss in prednisolone-treated mice

Oct. 9, 2023
While glucocorticoids are used as first-line therapy for Duchenne muscular dystrophy (DMD), these agents are associated with several adverse events, including accelerated bone loss and muscle atrophy. As a result, prolonged glucocorticoid treatment is one of the primary contributors to the high fracture rate in patients with DMD.
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