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BioWorld - Wednesday, April 8, 2026
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Cancer

Adcytherix raises $122M series A to develop novel ADCs

Oct. 17, 2025
By Nuala Moran
No Comments
A year and half from its inception, Adcytherix SAS has raised a €105 million (US$122 million) series A, enabling it to take the lead antibody-drug conjugate (ADC) program into clinical development next year.
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Cancer

Shenzhen Zhongge Biotechnology discovers new KIF18A inhibitors

Oct. 17, 2025
Shenzhen Zhongge Biotechnology Co. Ltd. has described kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Cancer

New TEAD inhibitors disclosed in Insilico Medicine patent

Oct. 17, 2025
Insilico Medicine Ltd. has divulged transcriptional enhancer factor (TEAD) inhibitors reported to be useful for the treatment of cancer and fibrosis.
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Endocrine/metabolic

Genescience Pharmaceuticals describes new PAH stabilizers for PKU

Oct. 17, 2025
Genescience Pharmaceuticals Co. Ltd. has identified phenylalanine hydroxylase (PAH) (R408W mutant) stabilizers reported to be useful for the treatment of phenylketonuria (PKU).
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Gastrointestinal

Salubris Pharmaceuticals divulges new MIR124 activators

Oct. 17, 2025
Shenzhen Salubris Pharmaceuticals Co. Ltd. has synthesized compounds acting as MIR124 activators reported to be useful for the treatment of inflammatory bowel disease and inflammatory disorders.
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Inflammatory

Bioage Labs patents new NLRP3 inflammasome inhibitors

Oct. 17, 2025
Bioage Labs Inc. has disclosed NLRP3 inflammasome inhibitors reported to be useful for the treatment of inflammatory disorders.
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Biomarkers

miR-1265 emerges as a biomarker of meningioma

Oct. 17, 2025
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Meningiomas are usually grade I benign tumors that can turn into aggressive grade II or III malignant tumors. Genome-wide methylation analysis has shown that microRNA 1265 (miR-1265) is hypermethylated in meningiomas.


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Kidneys and adrenal glands
Nephrology

Xortx to acquire VB4-P5 renal program from Vectus

Oct. 17, 2025
No Comments
Xortx Therapeutics Inc. has entered into a binding term sheet to acquire a renal anti-fibrotic therapeutic program from Vectus Biosystems Ltd., including a novel new chemical entity, VB4-P5.
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Fallopian tubes, ovaries and uterus
Biomarkers

AKR1B1 and AKR1B10 as prognostic markers in endometrial cancer

Oct. 17, 2025
No Comments
Endometrial cancer is the most prevalent gynecological malignancy in high-income countries, and the discovery of new biomarkers may aid in earlier detection and improve the prognosis of patients.
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Dermatologic

Readthrough of premature stop codons for epidermolysis bullosa

Oct. 17, 2025
No Comments
Researchers at the Keck School of Medicine at the University of Southern California explored whether CC-90009 can promote readthrough in the two types of epidermolysis bullosa.
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