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Stop-gain variant in GMIP gene tied to Alzheimer's disease pathogenesis

July 31, 2018

Arcus cleared to begin phase I trial of anti-TIGIT antibody AB-154

July 31, 2018

FDA approves Azedra for pheochromocytoma or paraganglioma

July 31, 2018

Janssen studies PRMT5 inhibitor JNJ-64619178 in advanced cancers

July 31, 2018

First-in-human study investigates CALR exon 9 mutant peptide vaccine in CALR-mutant MPNs

July 31, 2018

Dong-A conducts phase II study with DA-8010 in overactive bladder

July 31, 2018

Regenera initiates phase II study of RPh-201 in NAION

July 31, 2018

Phase III study of RHB-104 in Crohn's disease meets primary endpoint

July 31, 2018

Primary endpoints met in phase IIb study of PRX for presbyopia

July 31, 2018

Beta Cat studies BC-2059 for unresectable desmoid tumors in phase I

July 31, 2018

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SCAN is core circuit affected in Parkinson’s disease
BioWorld Science
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement, and tremor is one of its signatures. But it is a much more wide-ranging disorder,...
TL1A is overexpressed in hidradenitis suppurativa
BioWorld Science
Despite the availability of advanced therapeutic options, about 40%-50% of patients with hidradenitis suppurativa do not achieve significant improvement in...
IL-22 and TL1A, a robust couple for diagnosing hidradenitis suppurativa
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Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with strong association with psoriasis and inflammatory bowel disease (IBD). While some...
Astellas’ ASP-2246 shows promise in stroke management
BioWorld Science
Astellas Pharma Inc. recently presented data regarding ASP-2246, a drug candidate comprised of an mRNA encoding the transcription factor NeuroD1 encapsulated in...