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Cancer

New KIF18A inhibitors disclosed in Insilico Medicine patent

July 23, 2024
Insilico Medicine Inc. has divulged compounds acting as kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.
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Cancer

Asieris Pharmaceuticals describes new ATR inhibitors

July 23, 2024
Asieris Pharmaceuticals Co. Ltd. has identified serine/threonine-protein kinase ATR inhibitors reported to be useful for the treatment of cancer.
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Inflammatory

Immunophage Biomedical divulges new MIF inhibitors

July 23, 2024
Immunophage Biomedical Co. Ltd. has synthesized macrophage migration inhibitory factor (MIF) inhibitors reported to be useful for the treatment of cancer and inflammation.
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Cancer

Exelixis patents new PKMYT1 inhibitors

July 23, 2024
Exelixis Inc. has disclosed membrane-associated tyrosine- and threonine-specific Cdc2-inhibitory kinase (PKMYT1) inhibitors reported to be useful for the treatment of cancer.
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Silhouette made of crumpled paper illustrating depression
Neurology/psychiatric

Mira releases new data supporting Ketamir-2’s use for neuropsychiatric disorders

July 23, 2024
Mira Pharmaceuticals Inc. has released new preclinical study results for its oral ketamine analogue, Ketamir-2, which is under investigation for potential to treat neurological and neuropsychiatric disorders, including depression, treatment-resistant depression and post-traumatic stress disorder.
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Illustration of women's reproductive organs
Biomarkers

ZNF334 as diagnostic biomarker and therapeutic target in cervical cancer

July 23, 2024
Researchers from Chongqing Medical University and affiliated organizations reported findings from studies they performed to assess the role of zinc-finger protein 334 (ZNF334) in cervical cancer.
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Transmission electron micrograph of H1N1.
Infection

Discovery of potent pan-H1 monomeric nanobody with prophylactic activity against influenza infections

July 23, 2024
Researchers from CONICET and affiliated organizations presented the discovery of novel llama-derived single-chain antibody fragments (VHHs) specific for type A influenza virus.
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Cross-section of brain
Neurology/psychiatric

Delayed BTB-09089 treatment improves neurological functional recovery and brain tissue repair post-stroke

July 23, 2024
Researchers from Shanxi Medical University presented data from a study that aimed to assess the effects of delayed treatment with G protein-coupled receptor 65 (GPR65) agonist BTB-09089 on neurorestoration following ischemic stroke in mice.
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3D illustration and light micrograph of lung cancer.
Cancer

Mitocarex validates potential role of target SLC25 carrier protein in NSCLC

July 23, 2024
Scisparc Ltd.’s Mitocarex Bio Ltd. venture has validated the potential significant involvement of its target SLC25 carrier protein, using non-small-cell lung cancer (NSCLC) cells with diverse genetic backgrounds. Mitocarex used genetic manipulations and 3D spheroid systems, mimicking the main features of human solid tumors, to demonstrate the discovery.
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3D illustration showing presence of tumor inside prostate gland
Diagnostics

[68Ga]SDTWS-01, a PSMA-targeting radiotracer for the diagnosis of prostate cancer

July 23, 2024
Researchers from Shandong University and affiliated organizations reported the discovery and preclinical characterization of novel 68Ga-labeled PSMA-targeting tracers for the diagnosis of prostate cancer.
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