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BioWorld - Sunday, June 21, 2026
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Cancer

Shenzhen Zhongge Biotechnology identifies new NLRP3 inflammasome inhibitors

Sep. 12, 2024
Shenzhen Zhongge Biotechnology Co. Ltd. has discovered NLRP3 inflammasome inhibitors reported to be useful for the treatment of cancer, liver, cardiovascular, inflammatory, renal, metabolic and neuroinflammatory disorders.
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Cancer

Morphic Therapeutic describes new integrin αvβ8 antagonists

Sep. 12, 2024
Morphic Therapeutic Inc. has divulged integrin αvβ8 antagonists reported to be useful for the treatment of cancer.
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Three nasal spray containers
Neurology/psychiatric

Silo Pharma completes pre-IND meeting with FDA on SPC-15 for PTSD

Sep. 12, 2024
Silo Pharma Inc. has completed a pre-IND meeting with the FDA regarding the company’s development plan for SPC-15, an intranasal prophylactic treatment for post-traumatic stress disorder (PTSD) and stress-induced anxiety disorder.
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Brain and DNA
Neurology/psychiatric

Grant supports early studies of SBT-589 for Friedreich’s ataxia

Sep. 12, 2024
Stealth Biotherapeutics Inc. has been awarded the Kyle Bryant Translational Research Award from the Friedreich’s Ataxia Research Alliance (FARA) to evaluate mitochondria-targeted molecule SBT-589 in Friedreich’s ataxia (FA).
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Doctor points at molecular structure
Drug design, drug delivery & technologies

C4 Therapeutics delivers 2nd Bidac degrader to Biogen

Sep. 12, 2024
C4 Therapeutics Inc. has successfully delivered a second development candidate to Biogen Inc. under the companies’ 2018 strategic collaboration.
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Drug design, drug delivery & technologies

Gilead and Genesis collaborate on drug discovery

Sep. 12, 2024
Gilead Sciences Inc. and Genesis Therapeutics Inc. have entered into a strategic collaboration to discover and develop novel small-molecule therapies across multiple targets.
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Influenza A virus (H3N2)
Immune

TFF H1, H3 vaccine candidates produce protective antibodies in ferrets

Sep. 12, 2024
TFF Pharmaceuticals Inc. has announced promising preclinical data advancing a multivalent universal influenza vaccine manufactured by its Thin Film Freezing (TFF) technology to protect against seasonal and pandemic viruses.
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Endocrine/metabolic

Novo Nordisk exercises option to license Kallyope ligand for obesity

Sep. 12, 2024
Novo Nordisk A/S has exercised an option to license a ligand identified by Kallyope Inc. for further development, including as a potential new approach for the treatment of obesity.
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3d illustration of ovarian cancer
Immuno-oncology

Tunable antibody-drug conjugate tested in ovarian cancer model

Sep. 12, 2024
OS Therapies Inc. has announced promising data in animal models of ovarian cancer for its first therapeutic candidate developed based upon its proprietary tunable antibody-drug conjugate (tADC) platform.
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Kidneys
Nephrology

Keap1-Nrf2 interaction inhibitors show activity in rat kidneys

Sep. 12, 2024
Researchers from Japan Tobacco Inc. presented the discovery and preclinical characterization of novel highly potent Keap1-Nrf2 protein-protein interaction (PPI) inhibitors.
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