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BioWorld - Wednesday, July 15, 2026
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Infection

Hepaitech (Beijing) Biopharma Technology discovers MRGPRX4 antagonists

May 16, 2024
Hepaitech (Beijing) Biopharma Technology Co. Ltd. has patented compounds reported to be useful for the treatment of anemia, fungal infections and HIV infections, among others.
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Cancer

Medshine Discovery presents a new benzylaminoquinoline compound

May 16, 2024
Medshine Discovery Inc. has divulged GTPase KRAS (G12C mutant) Inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Haihe Biopharma identifies new PARP-1 inhibitors

May 16, 2024
Shanghai Haihe Biopharma Co. Ltd. has described poly(ADP-ribose) polymerase 1 (PARP-1) inhibitors reported to be useful for the treatment of cancer.
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Optogenetics illustration
Ocular

New subretinal gene therapy in rodent models of geographic atrophy

May 16, 2024
Researchers from Ikarovec Ltd. have presented preclinical data for the AAV8-IKC159V, the company’s lead bicistronic gene therapy being developed for the treatment of geographic atrophy, a late stage of geographic dry AMD.
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Molecule illustration
Drug design, drug delivery & technologies

Totus Medicines to discover small-molecule drug candidates against Lilly targets

May 16, 2024
Totus Medicines Inc. has entered into a multi-target research collaboration with Eli Lilly & Co. to discover small-molecule drug candidates against undisclosed targets in different therapeutic areas.
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3D illustration of tumor
Immuno-oncology

Grant supports Lift Biosciences’ evaluation of IMAN cell therapies in humanized in vivo model systems

May 16, 2024
Lift Biosciences Ltd. has been awarded a grant of over £1 million (US$1.3 million) from Innovate UK that will fund a collaboration between Lift and researchers at the University of Cambridge.
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Woman using eyedrops
Ocular

VIAN-c4551 could be eye drop alternative to anti-VEGF injections

May 16, 2024
Intravitreal VEGF inhibitors are the first-line treatment for vascular retinopathies, but they are invasive, painful and require frequent treatments.
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Close up of hand scratching arm with psoriasis patches
Biomarkers

BAG3 protein is present in serum from patients with psoriasis

May 16, 2024
Due to the systemic nature of psoriasis, there is high risk for progressive severe forms of the disease.
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Cancer tumor in breast illustration
Biomarkers

TRIM2 predicts poor survival in patients with TNBC on chemotherapy

May 16, 2024
Breast cancer is a heterogenous disease in terms of its prognosis and treatment response. Metabolic reprogramming is a potential therapeutic target because of its repercussion on oncogenesis.
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Nephrology

Glis2 targeting suppresses cyst formation in polycystic kidney disease models

May 16, 2024
Researchers from Yale School of Medicine, Ionis Pharmaceuticals Inc. and the National Institutes of Health have published data from a study that aimed to identify the signaling pathways involved in cilia-dependent cyst activation (CDCA) in autosomal dominant polycystic kidney disease (ADPKD).
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