Radiation therapy resistance (radioresistance) is a key contributor to the failure of rectal cancer treatment, with immunosuppression playing a significant role here.
23andme Holding Co. has received FDA clearance of its IND application for 23ME-01473 (‘1473), a dual mechanism antibody and natural killer (NK) cell activator intended to treat cancer.
Vivet Therapeutics SAS has been awarded financing of €4.9 million (US$5.3 million) from the French government to advance the development of a gene therapy for the treatment of the neurodegenerative disease cerebrotendinous xanthomatosis (CTX).
Guard Therapeutics AB has presented progress within the company’s preclinical development platform, the GTX platform, aimed at developing new peptides based on the endogenous protein α-1-microglobulin.
Perioperative neurocognitive disorders (PNDs) refer to a variety of cognitive abnormalities mainly experienced by elderly patients after anesthesia procedures and include cognitive impairment and disorientation linked to oxidative stress and neuroinflammation. Insulin-like growth factor-1 (IGF-1), a neurotrophic hormone that regulates microglia-mediated neuroinflammation, may represent a therapeutic target in this context.
Researchers from University of Lausanne have published data from a study that aimed to analyze the key components of the brain tumor vasculature in order to better understand the mechanisms of brain metastasis (BrM).
Vect-Horus SAS has entered into a license agreement providing Ionis Pharmaceuticals Inc. with a worldwide, exclusive license for a specified number of targets using Vect-Horus’ platform technology Vectrans for systemic delivery of RNA-targeted therapeutics that can cross the blood-brain barrier and address targets in the central nervous system.
Researchers from Chengdu Zeling Biomedical Technology Co. Ltd. and affiliated organizations presented the discovery of novel phosphatidylinositol 3‑phosphate 5‑kinase (PIKfyve) inhibitors being developed for the treatment of cancer.
Vaxxinity Inc. has announced a research collaboration with the University of Florida’s (UF) Center for Translational Research in Neurodegenerative Disease (CTRND) to support its work on the development of vaccines for neurodegenerative diseases.
Researchers from Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College have discovered novel selective Kv2.1 inhibitors as potential therapeutic candidates for the treatment of ischemic stroke.
RSS
