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BioWorld - Sunday, June 14, 2026
Home » Topics » Science » Drug design, drug delivery and technologies

Drug design, drug delivery and technologies
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Illustration of cell dividing
Drug Design, Drug Delivery & Technologies

Peptigrowth and Orizuru Therapeutics collaborate on synthetic growth factor for use in regenerative medicines

Aug. 24, 2023
Peptigrowth Inc. and Orizuru Therapeutics Inc. have entered into a joint development agreement to create a novel synthetic peptide that will replace a recombinant growth factor used in the manufacturing of a regenerative medicine product being developed by Orizuru.
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Attention deficit hyperactivity disorder brain connections illustration.
Neurology/Psychiatric

3Z and Biotx.ai partnership to utilize AI modeling to advance ADHD drug development

Aug. 21, 2023
3Z ehf and Biotx.ai AG have established a strategic partnership to help advance the development of drugs for attention deficit hyperactivity disorder (ADHD).
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Illustration of brain in head highlighting the blood-brain barier.
Endocrine/Metabolic

Chiesi and Aliada partner on blood-brain barrier-crossing platform technology for lysosomal storage disorders

Aug. 16, 2023
Chiesi Global Rare Diseases, a Chiesi Farmaceutici SpA business unit, has signed a co-development agreement with Aliada Therapeutics Inc.
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Gastrointestinal

Gut enzyme inhibitor could reduce inflammatory bowel disease symptoms

Aug. 16, 2023
By Mar de Miguel
A new drug that inhibits the glutamate carboxypeptidase II (GCPII) enzyme could be used to treat inflammatory bowel disease (IBD), according to a new study in mice and human organoids. After decades of research trying to design GCPII inhibitors against neurological disorders, the new compound could be effective for another use.
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Hourglass, sunset, silhouettes
Genetic/Congenital

Multivariate GWAS IDs healthy aging candidate genes

Aug. 8, 2023
Researchers have used multivariate statistical analysis to identify new genomic loci related to aging, and new potential drug targets. They reported their findings online in Nature Aging on Aug. 7, 2023. Aging is a multifaceted process, and whether it is going well or not is determined by multiple factors. Most aging studies, however, focus on individual aspects of aging.
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Art concept for gene therapy research
Drug Design, Drug Delivery & Technologies

Alexion, Astrazeneca Rare Disease agrees to acquire Pfizer’s preclinical rare disease gene therapy portfolio

July 31, 2023
Alexion, Astrazeneca Rare Disease, part of Astrazeneca plc, has entered a definitive purchase and license agreement for a portfolio of preclinical gene therapy programs and enabling technologies from Pfizer Inc.
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Electron micrograph of red blood cell infected with Plasmodium falciparum surrounded by knobless uninfected blood cells.
Infection

New mRNA malaria vaccine could be more effective than antibody strategies targeting liver memory T cells

July 27, 2023
An mRNA vaccine candidate that acts in the liver by recruiting memory T cells could be the key against malaria, according to a study in mice that demonstrated its efficacy by including a natural killer T (NKT) cell agonist.
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Drug Design, Drug Delivery & Technologies

Chroma and Sangamo sign agreement on epigenetic medicines leveraging zinc finger proteins

July 21, 2023
Sangamo Therapeutics Inc. and Chroma Medicine Inc. have entered into a research evaluation, option and license agreement to develop epigenetic medicines leveraging zinc finger proteins (ZFPs) for sequence-specific DNA recognition.
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Cells of the human intestine
Gastrointestinal

Human organ atlas maps healthy and diseased tissues at the cellular level

July 20, 2023
By Mar de Miguel
The Hubmap consortium has released the atlas of three human organs, a cell-by-cell map based on overlaid images from microscopy and molecular data. Maps of the intestine, the kidney and the placenta, published in three simultaneous articles, have revealed the cellular morphology and architecture of these organs in healthy and diseased conditions.
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3D illustration of a ribosome constructing messenger RNA molecules
Drug Design, Drug Delivery & Technologies

Even personalized drugs could benefit multiple patients

July 18, 2023
By Mar de Miguel
Using whole genome sequencing, scientists at Boston Children’s Hospital have studied the genes and mutations of ataxia-telangiectasia (A-T) that would respond to treatments with splice-switching antisense oligonucleotides (ASOs). Their work, published on July 12, 2023, in Nature, determined the appropriate individualized genetic therapy for these patients and identified a new drug.
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