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BioWorld - Friday, January 9, 2026
Home » Topics » Substance use and poisoning, BioWorld Science

Substance use and poisoning, BioWorld Science
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Illustration of pill being analyzed
Substance use and poisoning

GATC Health compounds enter preclinical development for fentanyl addiction and opioid use disorders

Oct. 7, 2022
GATC Health Corp. has announced that the new drug candidates discovered by its proprietary artificial intelligence (AI) drug discovery and prediction platform to treat opioid use disorder (OUD) and fentanyl addiction have entered preclinical development.
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Pipet, test tubes, chemical structure
Substance use and poisoning

Spironolactone shows promise for alcohol abuse disorder in rodents

Oct. 3, 2022
Recent evidence suggests that spironolactone, a mineralocorticoid receptor antagonist, may modulate alcohol seeking and consumption, for which current therapies are limited.
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Molecule illustration
Substance use and poisoning

NIAAA grant supports Epivario's work on ACSS2 inhibition for alcohol use disorder

Sep. 15, 2022
Epivario Inc. has been awarded a grant of nearly $260,000 from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to advance research on its proprietary small-molecule inhibitors designed to reduce alcohol craving responses and help people with alcohol use disorder (AUD) prevent relapse.
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MultiStem shows benefit in animal model of acute radiation syndome

Aug. 9, 2022
A radiation countermeasure study conducted by the Armed Forces Radiobiology Research Institute (AFRRI) has shown that intravenous administration of Athersys' MultiStem (invimestrocel) provided benefit in an animal model of acute radiation syndrome (ARS).
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M2-mAChRs as therapeutic targets for treating substance use disorders

July 28, 2022

Clearmind reports safety and reduced alcohol consumption with combination of MEAI and CannAmide

May 25, 2022

Clearmind's MEAI shows suppressive effect on alcohol consumption in mice

May 20, 2022

Novel selective D3R ligands for the treatment of drug addiction

May 19, 2022

M1 mAChR antagonism attenuates opioid drug seeking behaviors in rat

May 5, 2022

CNRS and collaborators patent acetylcholinesterase reactivators

April 1, 2022
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