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BioWorld - Friday, December 26, 2025
Breaking News: BioWorld 2025 Year in ReviewBreaking News: BioWorld MedTech 2025 Year in ReviewBreaking News: Trump administration impacts continue to roil the life sciences sector
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Dan Chen, founder and CEO, Synthetic Design Lab
Newco news

Synthetic Design emerges with $20M and next-gen ADC platform

April 24, 2025
By Jennifer Boggs
Synthetic Design Lab Inc., which emerged from stealth with a $20 million seed round and a platform technology aimed at advancing the antibody-drug conjugate (ADC) space, began with its founders identifying a single clear goal: how to deliver more payload to a target cancer cell.
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Genetic editing with CRISPR

Brink’s recombinase enzymes offer new gene editing approach

April 17, 2025
By Nuala Moran
Newco Brink Therapeutics SAS is poised to work on the next chapter in genome editing after raising €3.5 million (US$4 million) in seed funding to discover and develop programmable recombinase enzymes.
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Illustration of antibodies attacking neurons
Newco news

Aiming for autoimmunity, Merida Bio launches with $121M series A

April 8, 2025
By Karen Carey
When an autoimmune disease disrupted the life of someone close to scientist Dario Gutierrez, an idea emerged for a new company called Merida Biosciences focused on removing misdirected antibodies and their negative effects using Fc biotherapeutics.
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Feet on scale
Newco news

Antag aiming to fill therapeutic gaps in obesity space

April 3, 2025
By Nuala Moran
The latest obesity contender, Antag Therapeutics A/S, has dosed the first participants in a phase I trial of a glucose-dependent insulinotrophic polypeptide (GIP) agonist it said will address key gaps in the current treatment options, not least the gastrointestinal side effects seen with GLP-1 agonists.
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Newco news

Hillstar launches with $67M series A to target TRBV9+ T cells

March 25, 2025
By Brian Orelli
Hillstar Bio came out of stealth mode, announcing a $67 million series A financing round with investors including Droia Ventures, Frazier Life Sciences, Novo Holdings A/S and Lifearc Ventures.
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3D dollar sign

Augustine Therapeutics closes $85M series A for HDAC6 inhibitors

March 24, 2025
By Nuala Moran
Eight months after announcing the $18.5 million first tranche of its series A, Augustine Therapeutics has closed the oversubscribed round at $85 million and is now ready to begin clinical development of its novel histone deacetylase-6 (HDAC6) inhibitors.
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Colorized scanning electron microscope image of regulatory T cells and antigen-presenting cells.
Newco news

Japan’s Regcell launches in US with $45.8M to advance Treg platform

March 18, 2025
By Tamra Sami
Japanese-founded Regcell Inc. has raised $45.8 million and is redomiciling to the U.S. to accelerate clinical development of its pioneering regulatory T-cell (Treg) platform for autoimmune diseases and transplantation.
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Sofinnova adds €165M to boost European startups

March 18, 2025
By Nuala Moran
Leading pharma companies have pitched into Sofinnova Partners’ new accelerator fund, which has exceeded the target and closed at €165 million (US$180 million). In what is said to be the largest pan-European biotech accelerator fund, Amgen Inc., Bristol Myers Squibb Co. and Pfizer Ventures will get an inside track on startups formed around academic research, as the nascent companies are shaped up for formal investment rounds.
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Astellas Yaskawa Maholo

Astellas-Yaskawa JV to build robot-based cell production platform

March 6, 2025
By Marian (YoonJee) Chu
Astellas Pharma Inc. is setting up a joint venture with Yaskawa Electric Corp. to develop a new cell production platform using Yaskawa’s dual-arm humanoid robot called Maholo.
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3D rendering of drug linked to antibody

Hummingbird migrates ADCs, tech to newco Callio’s $187M debut

March 4, 2025
By Marian (YoonJee) Chu
Antibody-drug conjugate (ADC)-focused Callio Therapeutics debuted on March 3 with the closing of a $187 million series A financing round based on cancer drug technology and assets in-licensed from Hummingbird Bioscience Pte Ltd.
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