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BioWorld - Friday, February 20, 2026
Breaking News: BioWorld 2025 Year in ReviewBreaking News: Trump administration impacts continue to roil the life sciences sector
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Appointments and advancements for Oct. 23, 2025

Oct. 23, 2025
New hires and promotions in the biopharma industry, including: Alvotech, Basking, Calidi, Cassava, Electra, Promis, Sironax.
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Moderna’s cytomegalovirus vaccine fails a phase III

Oct. 23, 2025
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A preview of the next edition of BioWorld, Oct. 23, 2025
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Regulatory actions for Oct. 23, 2025

Oct. 23, 2025
Regulatory snapshots, including global drug submissions and approvals, and other regulatory decisions and designations: Adarx, Amgen, Astellas, Astrazeneca, Boehringer Ingelheim, Electra.
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Other news to note for Oct. 23, 2025

Oct. 23, 2025
Biopharma happenings, including deals and partnerships, and other news in brief: AAX, Biossil, Daiichi Sankyo, Forlong, Galera, Henlius, Kyowa Kirin.
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In the clinic for Oct. 23, 2025

Oct. 23, 2025
Clinical updates, including data readouts and publications: ACM Biolabs, Alector, Arcturus, Astellas, Dynavax, Iaso, Nanoscope, Novartis, OS Therapies, Perspective, Puretech, Sanofi, Terns.
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BIX 2025

Opportunity, risks of cell therapy to tackle aging and disease

Oct. 23, 2025
By Marian (YoonJee) Chu
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Stem cells are a promising therapeutic modality to fight aging and age-related disease, speakers at the Bio-Plus Interphex Korea 2025 said. Progress in cell-based longevity medicine is being made, they added, although safety, ethical and regulatory issues are ongoing challenges.
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Ena Respiratory's INNA-051

Ena Respiratory raises AU$34M series B to fund phase II trial

Oct. 23, 2025
By Tamra Sami
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Ena Respiratory Pty Ltd. raised an AU$34 million (US$22.4 million) series B round to advance INNA-051, its nasal spray for symptomatic viral respiratory infections, to phase II trials. New investors in the Melbourne-headquartered company include the Gates Foundation and Flu Lab. Existing investors Brandon Capital, Uniseed and Stoic Venture Capital also participated in the round.
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NLRP3 inflammasome

Risk intolerance: Ventyx CV bid shines in NLRP3 phase II

Oct. 23, 2025
By Randy Osborne
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Ventyx Biosciences Inc. rolled out positive results from the phase II study with oral, once-daily VTX-3232 in patients with obesity and cardiovascular (CV) risk factors.
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Acquisition target

Ipsen to acquire fellow French company Imcheck in €1B deal

Oct. 23, 2025
By Nuala Moran
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Ipsen SA is expanding its cancer portfolio with the €1 billion (US$1.16 billion) acquisition of immuno-oncology specialist Imcheck SAS, and will pay €350 million up front with the balance to come in regulatory and sales-based milestones for the lead program ICT-01.
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Moderna signage

Moderna’s cytomegalovirus vaccine fails a phase III

Oct. 23, 2025
By Lee Landenberger
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Moderna Inc. stopped its efforts to develop mRNA-1647 as a vaccine for preventing congenital cytomegalovirus infection, the most common infectious cause of birth defects in the U.S. The pivotal and placebo-controlled phase III CMVictory study of mRNA-1647 missed the primary efficacy endpoint, which was preventing the infection in seronegative females ages 16 to 40.
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