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BioWorld - Thursday, April 30, 2026
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Cancer cells being destroyed by immunotherapy
Newco news

Avidicure boosting immune activation with $50M seed round

May 15, 2025
By Nuala Moran
No Comments
Newco Avidicure NV arrived on the scene with a hefty $50 million in seed funding to advance novel antibody formats the company says will surpass the best qualities of first-generation antibodies, checkpoint inhibitors, T-cell engagers and antibody-drug conjugates.
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Pills arranged in dollar sign

US threat of most-favored-nation Rx pricing intensifies

May 15, 2025
By Mari Serebrov
No Comments
Recognizing the potential legal challenges to U.S. President Donald Trump’s executive order calling for most-favored-nation (MFN) prescription drug pricing and the limits of that order, several congressional Democrats introduced a bill in both the House and Senate May 14 that could make MFN pricing the law of the land and extend it to both government health programs and private insurance.
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Inozyme’s INZ-701 shows promise for rare disease ENPP1 deficiency

May 15, 2025
By Karen Carey
No Comments
Just two months after Inozyme Pharma Inc. cut its workforce by 25% and prioritized activities to focus on a BLA filing for INZ-701 for ENPP1 deficiency, interim phase III data from its Energy 3 trial showed consistent safety and immunogenicity and increased phosphate levels in patients treated with the rare disease enzyme replacement therapy.
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Children’s Hospital of Philadelphia
ASGCT 2025

First bespoke gene editing therapy treats rare metabolic disease

May 15, 2025
By Anette Breindl
No Comments
Using a customized gene editing therapy, researchers at the Children’s Hospital of Philadelphia have reported success in treating an infant with a severe metabolic disorder. Kiran Musunuru, Barry J. Gertz Professor for Translational Research in the University of Pennsylvania’s Perelman School of Medicine, presented the case at the American Society of Gene and Cell Therapy’s 2025 annual meeting. The case study was simultaneously published in The New England Journal of Medicine.
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Lung cancer illustration

US FDA clears Abbvie’s c-Met lung cancer ADC

May 14, 2025
By Karen Carey
No Comments
The U.S. FDA granted Abbvie Inc. accelerated approval for antibody-drug conjugate (ADC) Teliso-V (telisotuzumab vedotin), newly branded Emrelis, making it the first treatment for previously treated advanced non-small-cell lung cancer with high c-Met protein overexpression.
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Regulatory actions for May 14, 2025

May 14, 2025
Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Beam, Hyundai, Regenxbio, Sarepta.
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Other news to note for May 14, 2025

May 14, 2025
Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Abtherx, Affimed, AFT, Bayer, Endo, Galapagos, Hyloris, Intron, Leap, Mallinckrodt, Qliniq, Single Cell, Vaccinex.
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In the clinic for May 14, 2025

May 14, 2025
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Ascendis, Atea, Biorestorative, Cytodyn, Cytokinetics, Enterobiotix, Iteos, Karyopharm, Mediwound, Novo Nordisk, Roche.
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Financings for May 14, 2025

May 14, 2025
Biopharmas raising money in public or private financings, including: Altimmune, Axsome, Marvel, Neumora, Omeros, Remedy Plan, Sangamo, Stylus.
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Appointments and advancements for May 14, 2025

May 14, 2025
New hires and promotions in the biopharma industry, including: Compugen, Eleva, Galapagos, Hansa, Orca Bio, Sonoma, Syndax.
Read More
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