Bone Therapeutics SA raised €7.7 million (US$10.4 million) in new financing as a prelude to a larger round, as it seeks to expand the indication range for its cell therapy product Preob.

Cytox Ltd. has been rescued from liquidation and raised £3.5 million (US$5.5 million) in new money to reinvigorate efforts to develop a simple, definitive blood test for the early diagnosis of Alzheimer's disease.

With data due from a pivotal Phase III trial of its lead drug candidate around midyear, Gene Signal International SA raised an undisclosed investment from its longstanding syndicate of private investors to keep its pipeline of antisense and peptide-based drugs moving forward.

• Sirtex Medical Ltd., of New South Wales, Australia, reported results from an analysis of 548 patients in a clinical study testing Selective Internal Radiation Therapy (SIRT) with SIR-Spheres microspheres in patients with metastatic colorectal cancer.

Shares in Active Biotech AB fell almost 13 percent Monday on news that its immunotherapy Anyara missed the primary endpoint of a Phase II/III trial in advanced renal cell cancer.

ThromboGenics NV and its partner, the Alcon unit of Novartis AG, received a positive opinion from the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) for Jetrea (ocriplasmin) as a treatment for vitreous macular traction, paving the way for a European launch in the second quarter.

For 60 years, the DNA double helix has provided an iconic image of how our genetic information is held and how it reproduces. Now scientists at the University of Cambridge in the UK – where Watson and Crick developed their ideas about the genetic code – have provided another pioneering insight into the workings of human genes.

Newly established Dutch start-up Dezima Pharma BV in-licensed what it considers a best-in-class cholesteryl ester transfer protein (CETP) inhibitor, DEZ-001 (formerly TA-8995), from Osaka, Japan-based Mitsubishi Tanabe Pharma Corp. and is planning to move the cholesterol-lowering drug into a Phase II trial involving more than 400 patients in the coming months.

With key regulatory and clinical events fast approaching, MolMed SpA is set to add about €5 million (US$6.5 million) to its balance sheet in a capital increase that is fully underwritten in all but name.

The latest advance in antibody technology has arrived in the shape of the Crescendo mouse, a transgenic mouse that is engineered to generate fully human single domain VH fragments.