After developing new methods for analyzing structurally complex regions of the genome, researchers have gained new insights into the genetics of obesity.
Scientists at German biotech Curevac GmbH have reported they were able to raise erythropoietin (EPO) levels in pigs by treating them with sequence-engineered but chemically unmodified messenger RNA (mRNA) encapsulated in lipid nanoparticles.
Researchers have reported success in understanding why some attempts to vaccinate against mucosal pathogens have backfired, leading to worse disease instead of protecting the vaccines.
An anti-infective response of the innate immune system slows down wound healing, and the effect is exacerbated in diabetic mice, according to studies published this week.
In the biopharma world, prostaglandins are best known as a target for painkillers. Nonsteroidal anti-inflammatory drugs (NSAIDS) from ibuprofen to Celebrex (celecoxib, Pfizer Inc.) work by inhibiting the production of prostaglandin E2 (PGE2).
Students in medical school are sometimes told that only half of what they are learning is true, but, unfortunately, their teachers don't know which half.
BOSTON – Overall, physicians and patients can take heart from the results of two cardiovascular outcomes trials presented at the 75th annual meeting of the American Diabetes Association.
Scientists made progress toward the goal of mammalian tissue regeneration with the publication of studies showing that mice could be induced to self-repair ear wounds by a drug treatment that increased levels of the transcription factor HIF-1alpha.
For antimicrobials, toxicity and the ability to prevent resistance from evolving are widely considered two sides of the same coin. But researchers from the University of Illinois at Urbana-Champaign and The Whitehead Institute have shown that it is possible to separate those two aspects of drugs.
