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BioWorld - Sunday, July 12, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

Personalized medicine on rise but challenges still exist

May 26, 2015
By Brian Orelli
"Personalized medicine," "precision medicine," "pharmacogenomics" or whatever you want to call it, it's pretty clear the industry is moving in the direction of having drugs to treat patients based on their genetic makeup.
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Nurturing a promising new technology – the 'Moderna' way

May 18, 2015
By Brian Orelli
Biotechs often set up subsidiaries to house assets for tax reasons or to house programs unrelated to their core mission that might get spun off, but Moderna Therapeutics Inc. has a new twist, establishing "venture companies" focused on specific diseases.
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As IPO market wanes, biotechs turn to reverse mergers

May 11, 2015
By Brian Orelli
Through the first four months of the year, BioWorld Snapshots tracked 24 IPOs by drug companies on U.S. and international exchanges compared to 36 in the same time period last year.
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Nano steps for next-generation targeting nanomedicine tech

April 24, 2015
By Brian Orelli
As with any new technology, it takes baby steps to get drugs through the regulatory process and onto the market. And nanomedince is no exception. The technology is certainly progressing, but at a methodical pace.
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Nano steps for next-generation targeting nanomedicine tech

April 20, 2015
By Brian Orelli
As with any new technology, it takes baby steps to get drugs through the regulatory process and onto the market. And nanomedince is no exception. The technology is certainly progressing, but at a methodical pace.
Read More

Despite availability of equity capital, royalty deals abound

April 13, 2015
By Brian Orelli
In spite of increased biotech valuations providing for access to capital through the equity markets, the market for capital from the sale of royalties and structured debt tied to product sales is as hot as it's ever been.
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VCs start 2015 off with a bang, IPOs more like a whimper

April 2, 2015
By Brian Orelli
Neither snow in Boston nor a drought in California could stop venture capitalists from handing out cash in the first quarter to start-ups and established private companies alike.
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Cystic fibrosis firms highlight precision medicine's potential

March 30, 2015
By Brian Orelli
With different mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) causing different severities of the disease and requiring different drugs to increase protein function, cystic fibrosis (CF) is the poster child of precision medicine.
Read More

The other March Madness: Data from ACC (the heart one)

March 23, 2015
By Brian Orelli
Like the basketball Atlantic Coast Conference, the other ACC, the American College of Cardiology, ramps up this time of year with its annual scientific session.
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New spin on thin: CVOT and orphan data, ANDAs filed

March 16, 2015
By Brian Orelli
In drug development, it can be difficult to follow the crowd. And that goes double for a market like obesity that's struggled to gain traction.
Read More
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