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BioWorld - Friday, July 17, 2026
Home » Authors » Brian Orelli

Articles by Brian Orelli

Partnerships key for up-and-coming African biotechs

June 27, 2014
By Brian Orelli
SAN DIEGO – At the BIO International Convention, BIO Ventures for Global Health (BVGH) announced a partnership with the National Universities Commission (NUC) of Nigeria to place Nigerian academics at pharmaceutical and biotech companies.
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Accessing biodefense funding, experts to share experiences

June 16, 2014
By Brian Orelli
In a Thursday session at BIO 2014 next week, attendees will get a lesson from a panel of experts on how to get a piece of the government funding available for companies developing medical countermeasures (MCMs).
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Accessing biodefense funding, experts to share experiences

June 16, 2014
By Brian Orelli
In a Thursday session at BIO 2014 next week, attendees will get a lesson from a panel of experts on how to get a piece of the government funding available for companies developing medical countermeasures (MCMs).
Read More

Want data from the FDA? There's an app for that

June 9, 2014
By Brian Orelli
Last week, the FDA launched OpenFDA, an initiative to make public FDA data available through an application program interface (API), which allows mobile phone app and web developers to access the data directly and present them on websites and mobile apps.
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Reproducibility of experiments key for progress, investments

May 27, 2014
By Brian Orelli
It's hard to build up scientific knowledge and search for targeted drugs if the foundation isn't solid. But that's exactly what companies have found over the years.
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High priced cancer drugs not translating into lofty revenue

May 12, 2014
By Brian Orelli
The average cost per month for a branded oncology drug treatment in the U.S. is about $10,000, around double where it was a decade ago, according to a new report by IMS Institute for Healthcare Informatics.
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Specialty pharma sector hot on M&A, tax savings, products

May 5, 2014
By Brian Orelli
One sure sign that specialty pharma sector M&A is on fire: companies in the process of closing acquisition deals are acquiring companies while they wait for antitrust regulators to sign off on their deal.
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Small firms targeting therapies at the complement system

April 28, 2014
By Brian Orelli
The complement system is designed to kill pathogens through a signal cascade that results in cell lysis, removal of the pathogens through phagocytosis, and alerting other immune system cells to help with infections. Signals come from three different pathways – classical, lectin and alternative – culminating at the C3 protein of the cascade.
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Small firms targeting therapies at the complement system

April 21, 2014
By Brian Orelli
The complement system is designed to kill pathogens through a signal cascade that results in cell lysis, removal of the pathogens through phagocytosis, and alerting other immune system cells to help with infections. Signals come from three different pathways – classical, lectin and alternative – culminating at the C3 protein of the cascade.
Read More

Maximizing returns on proof of concept oncology trials

April 14, 2014
By Brian Orelli
SAN DIEGO – When designing phase II proof of concept trials, companies want to maximize the chance of seeing a signal. Avoiding so-called type III errors – trials that would have been successful but were never performed – leads to a "no drug left behind" mentality, Cong Chen, director of biostatistics and research decision science at Merck & Co. Inc. told the audience during a panel at the American Association for Cancer Research meeting last week.
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