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Home » Newsletters » BioWorld

BioWorld

March 31, 2020

View Archived Issues
Deal-handshake-wire-frame.png

Sitryx banks $60M in immunometabolism drug deal with Lilly

DUBLIN – Without particularly looking for a deal, immunometabolism specialist Sitryx Ltd. landed quite a large one – a licensing agreement in autoimmune disease with Eli Lilly and Co. involving up to four preclinical programs, for which it is receiving $50 million up front, $10 million as equity investment and up to $820 million in development milestones. Read More

Akero arrow sights gold, nearing pivot point in NASH?

Akero Therapeutics Inc. rolled out stellar non-COVID-19 (for a change) clinical news with long-acting fibroblast growth factor 21 (FGF21) analogue AKR-001 in biopsy-confirmed nonalcoholic steatohepatitis (NASH), but even in liver disease the pandemic became part of the discussion. Read More
Coronavirus stock market

Biopharma equities start to recover as financial markets stabilize

After plunging dramatically at the beginning of the month, biopharmaceutical equities appear to be recovering some of the valuation they originally lost when the financial markets cratered. As the curtain closed on a very turbulent month that most investors will want to forget, the BioWorld Biopharmaceutical index finished up 0.75%, but down about 2% for the year. Read More

Amarin stock plummets on district court’s patent ruling on Vascepa

A U.S. district court in Nevada ruled in favor of two ANDA filers in Amarin Corp. plc.’s patent litigation case regarding its fish oil cardiovascular therapy franchise, Vascepa (icosapent ethyl), increasing the possibility of generics crowding Amarin’s U.S. sales. Read More
Kidneys

AM-Pharma set for phase III with additional $52M round, but faces COVID-19 delays

LONDON – AM-Pharma BV raised a further $52 million for the phase III trial of its recombinant alkaline phosphatase product, Recap, in treating sepsis-associated acute kidney injury (AKI), but now faces a delay in starting the study, as the COVID-19 crisis takes up more and more clinical resources. Read More
Test-tube-dropper-research

Shionogi forms JV with Ping An to expand in China and targets immuno-oncology for next venture

BEIJING – Osaka-based Japanese infectious disease specialist Shionogi & Co. Ltd. said it will partner with Chinese insurance giant Ping An to establish a data-driven joint venture to develop new drugs in a deal involving ¥33.53 billion (US$311 million). It also plans to tap into immuno-oncology to address the patent cliff of its HIV drugs. Under the terms, the Japanese pharma will sell a 2.05% voting stake, or 6.35 million shares of its common stock, to Ping An for ¥33.53 billion. Shionogi will own 51% of the joint venture while Ping An owns 49%, Shionogi IR group manager Kunihiro Mera told BioWorld. Read More
Coronavirus-spike-3d-model

Structural studies show similarities and differences in SARS, COVID-19 receptor binding

LONDON – Two papers published online in Nature following accelerated peer review provide fine detail of how the spike protein on the COVID-19 coronavirus binds to the angiotensin converting enzyme 2 (ACE2) through which it infects its human host. Read More

Appointments and advancements for March 31, 2020

New hires and promotions in the biopharma industry, including: Alimera, Biosig, Brainstorm, Cambrex, Cybrexa, PCI, Redpin, Sofinnova. Read More

Conference data for March 31, 2020: ACC.20/WCC Virtual

New and updated preclinical and clinical data presented by biopharma firms at the American College of Cardiology’s 69th Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC Virtual), including: Amarin, Mesoblast, Resverlogix. Read More

Financings for March 31, 2020

Biopharmas raising money in public or private financings, including: Affinia, Ampersand Capital, Cytodyn, Equillium, Oncology Venture, Propanc, Vaccinex, Zealand, Zucara. Read More

In the clinic for March 31, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Akero, Bausch, Biocardia, Biomx, Chimed, Dicerna, Eyegate, Genfit, GT Biopharma, Iterum, Kiniksa, Matinas, Mersana, Mimetogen, Orphomed, Proqr, Reata, Synairgen, Verona, Xenon. Read More

Other news to note for March 31, 2020

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Abbvie, Anavex, Bionomics, Boehringer Ingelheim, Brii, Carterra, Cytomx, Dyne, Evotec, Excellabio, Gedeon Richter, Genfit, Green Cross, Horizon, Ildong, Immunoprecise, Index, Junshi, Kleo, Lee’s Myovant, Newron, Nuvo, Oxford, Orgenesis, Otsuka, Pharmahungary, Phio, Predictive, Primmune, SAB, Sirona, Takeda, Vaxart, VBI, Viscient, Windtree. Read More

Regulatory actions for March 31, 2020

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: AB Science, Agios, Astrazeneca, Bluebird, BMS, Cytodyn, Essa, GW, Intellia, Takeda, Zealand. Read More

Regulatory front for March 31, 2020

The latest global regulatory news, changes and updates affecting biopharma, including: Pfizer Healthcare India. Read More

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