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BioWorld - Thursday, April 23, 2026
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Home » Phase II-to-III transfer protocol unriddled? Newamsterdam writing new book of ester in anti-lipid class
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Phase II-to-III transfer protocol unriddled? Newamsterdam writing new book of ester in anti-lipid class

June 13, 2023
By Randy Osborne
Since late 2006, when hiked levels of aldosterone and increases in blood pressure foiled Pfizer Inc.’s torcetrapib, researchers have been wary of cholesteryl ester transfer protein (CETP) inhibitors. But not all researchers. Among the still-hopeful is Newamsterdam Pharma NV, which recently rolled out positive phase II data with obicetrapib, and the company is forging ahead despite other CETPs that have not fared well in late-stage testing after performing nicely in phase II, including candidates from Merck & Co. Inc. and Eli Lilly and Co.
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