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BioWorld - Sunday, July 12, 2026
Home » heart failure

Articles Tagged with ''heart failure''

cardiopulmonary support cannula
Patents

UCLA researchers file patent for cardiopulmonary support cannula

Sep. 23, 2024
By Simon Kerton
Researchers from UCLA’s Department of Cardiac Surgery filed for protection of a smart multistage peripherally inserted cannula with active fixation for temporary cardiopulmonary support which simultaneously drains both sides of the heart.
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Illustration of heart and lung vasculature in pulmonary hypertension vs. normal
Cardiovascular

Effect of COR-1389 on cardiopulmonary function in pulmonary hypertension associated with right heart failure

Sep. 6, 2024
Researchers from Corteria Pharmaceuticals SAS and Université Paris-Saclay recently presented the preclinical results on a long-acting corticotropin-releasing factor CRF2 receptor agonist, COR-1389.
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Man clutching heart
Cardiovascular

Pfizer presents data on PF-07328948 for the treatment of heart failure

Sep. 5, 2024
Essential branched-chain amino acids (BCAA) such as leucine, isoleucine or valine, cannot be synthesized by mammals, making them an obligate part of the diet.
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Product image

Abbott’s Mitraclip third trial: Triumph, TEERs and nuanced results

Sep. 4, 2024
By Annette Boyle
Hope for definitive resolution of the controversy about the superiority of transcatheter edge-to-edge repair of mitral valves over medical therapy in individuals with symptomatic heart failure and functional mitral regurgitation were dashed at the European Society of Cardiology meeting this weekend.
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Heart illustration
Cardiovascular

Ghrelin receptor agonist improves cardiac function in preclinical heart failure

Sep. 3, 2024
At the recent European Society of Cardiology meeting, Anacardio AB and Helsinn Healthcare SA presented data on their oral small-molecule ghrelin receptor agonist and first-in-class calcium sensitizing inotrope, AC-01, in preclinical models of heart failure.
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Cardiovascular

Glucagon receptor antagonism’s beneficial effect on heart failure described

Aug. 27, 2024
Heart failure with preserved ejection fraction (HFpEF) is associated with hypertension and metabolic disorders and remains one of the main challenges for cardiovascular risk management. Researchers from the University of Cincinnati, Duke University School of Medicine, Remd Biotherapeutics Inc. and collaborators described the use of targeted inhibition of glucagon signaling as a potential strategy to rescue the pathological features of HFpEF.
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johnson & johnson

J&J pumps up cardiac commitment with $1.7B V-Wave acquisition

Aug. 20, 2024
By Annette Boyle
Johnson & Johnson aims to add a fourth cardiac business to its portfolio in less than two years with the acquisition of V-W aveLtd., which makes the Ventura interatrial shunt system for the treatment of heart failure. J&J will pay $600 million up front and an additional $1.1 billion contingent on meeting specified regulatory and commercial milestones. The deal is slated to close before the end of the year.
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V-Wave

J&J pumps up cardiac commitment with $1.7B V-Wave acquisition

Aug. 20, 2024
By Annette Boyle
Johnson & Johnson (J&J) aims to add a fourth cardiac business to its portfolio in less than two years with the acquisition of V-Wave Ltd., which makes the Ventura interatrial shunt system for the treatment of heart failure. J&J will pay $600 million up front and an additional $1.1 billion contingent on meeting specified regulatory and commercial milestones. The deal is slated to close before the end of the year.
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3D illustration of heart cross section
Cardiovascular

H2S donor enhances SGLT2 inhibition in heart failure

July 18, 2024
Heart failure (HF) accounts for 9.2% of all cardiovascular-related deaths. HF with preserved ejection fraction (HFpEF) occurs when the left ventricular ejection fraction (LVEF) is ≥50%.
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intracardiac pulsatile ventricular assist device
Patents

Researchers develop intracardiac pulsatile ventricular assist device

June 27, 2024
By Simon Kerton
Researchers from the University of South Florida developed a novel ventricular assist device that is placed directly inside a failing ventricular cavity to help it pump blood correctly again. This device consists of a self-expanding stent that contains a sac and inlet/outlet ports that allow compression fluids to generate contractile forces that pump the blood out.
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