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BioWorld - Monday, July 13, 2026
Home » heart failure

Articles Tagged with ''heart failure''

CGM sensor
Patents

Patent filed for multiweek, multitarget CGM-like wearable sensor

April 10, 2025
By Simon Kerton
Researchers from the University of Cincinnati filed for protection of an electrochemical aptamer-based biosensor technology with improved sensitivity and longevity, which has the potential for monitoring several biomarkers over sustained periods.
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Colorful illustration of the heart
Cardiovascular

Injectable hydrogel with miR-222 EVs improves ischemia-reperfusion injury and cardiac remodeling

April 3, 2025
Regenerative heart therapy, integrating biocompatible materials with nucleic acids, proteins and live cells, offers a promising personalized approach to treating cardiac ischemic reperfusion injury and heart failure.
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Black and white arrows merging into one

Ajax, Boston Sci partner to develop new heart failure treatment

March 5, 2025
By Annette Boyle
Ajax Health LLC, with backing from the $4 billion KKR Health Care Strategic Growth Fund II, and Boston Scientific Corp. launched a new business, Flowmod, to advance a system for treating heart failure developed by Boston Sci.
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Berlin Heals raises funds for device to reverse heart failure

Feb. 24, 2025
By Shani Alexander
Berlin Heals Holding AG recently raised over CHF7 million (US$7.8 million) in a financing round for C-MIC, a small implantable device it believes can reverse heart failure.
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Cardiovascular

TLT-101 cBIN1 gene therapy reverses heart failure in animal models

Feb. 20, 2025
Researchers from Tikkunlev Therapeutics Inc. and the University of Utah have presented preclinical data on TLT-101, a gene therapy consisting of an adeno-associated virus serotype 9 (AAV9) vector encoding cardiac bridging integrator 1 (cBIN1) designed for the treatment of heart failure.
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Roche building

​US FDA clears Roche’s preeclampsia test

Feb. 14, 2025
By Annette Boyle
With rates of preeclampsia skyrocketing, the U.S. FDA’s510(k) clearance of Roche Holding AG’s Elecsys test for preeclampsia offers some hope of reducing the number of women and infants who die or experience life-long consequences from the development of dangerously high blood pressure during late pregnancy and in the days immediately following delivery.
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Colorful illustration of the heart
Cardiovascular

Parkin activation through PR-364 preserves cardiac function after acute MI in preclinical models

Feb. 13, 2025
Heart disease remains the leading cause of death worldwide, and developing new therapeutic approaches constitutes an urgent healthcare priority. Almost one-third of patients surviving myocardial infarction (MI) develop heart failure (HF), in part due to damage caused by the accumulation of dysfunctional mitochondria.
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Heart patch produced from induced pluripotent stem cells derived heart muscle cells in a collagen hydrogel
Cardiovascular

For the 99%, allografts can patch up failing heart

Jan. 31, 2025
By Anette Breindl
Implanted patches of iPS cell-derived heart muscle integrated with heart tissue in a primate model of heart failure, and in patients being treated in a clinical trial, marks progress toward a potential option for patients with advanced heart failure.
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Heart patch produced from induced pluripotent stem cells derived heart muscle cells in a collagen hydrogel
Cardiovascular

For the 99%, allografts can patch up failing heart

Jan. 30, 2025
By Anette Breindl
Implanted patches of iPS cell-derived heart muscle integrated with heart tissue in a primate model of heart failure, and in patients being treated in a clinical trial, marks progress toward a potential option for patients with advanced heart failure.
Read More
Cardiovascular illustration
Cardiovascular

VASN knockout induces myocardial fibrosis in mice, study shows

Jan. 30, 2025
Myocardial fibrosis is a key process for heart failure development that may lead to severe phenotypes, including cardiac arrest or sudden death. Vasorin (VASN) is a protein with high expression in the cardiovascular system and its upregulation had been found to protect smooth muscle cells from calcification.
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