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BioWorld - Sunday, March 22, 2026
Home » prostate cancer

Articles Tagged with ''prostate cancer''

Cancer

Montelino Therapeutics discovers new AR-v7-targeting PROTACs for prostate cancer

April 6, 2023
Montelino Therapeutics LLC has described proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety coupled to an androgen receptor variant 7 (AR-v7)-targeting moiety through a linker. They are reported to be useful for the treatment of cancer.
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Radiotherapy of cancer
Radioactive revolution

How equipped are radiopharma stakeholders to overcome radioactive challenges?

April 4, 2023
By Tamra Sami
Global interest in radiopharmaceuticals is growing, and some big deals in the space have sparked interest in the last few years. Novartis AG has spent about $6 billion in acquisitions and is seen as the global leader.
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Woman receiving radiotherapy treatments for cancer
Radioactive revolution

Disrupting the oncology space

April 4, 2023
By Tamra Sami
After spending decades developing targeted chemotherapy and bringing a dozen or so compounds into the clinic, Fusion Pharmaceuticals Inc. Chief Scientific Officer Christopher Leamon switched careers to focus on radio-oncology because he saw the need for “a really strong bomb to target cancer to get it to respond.” That was radiotherapy, said Leamon, who was one of the scientific founders of Endocyte Inc., which Novartis AG acquired.
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Radiotherapy of cancer
Radioactive revolution

How equipped are radiopharma stakeholders to overcome radioactive challenges?

April 3, 2023
By Tamra Sami
Global interest in radiopharmaceuticals is growing, and some big deals in the space have sparked interest in the last few years. Novartis AG has spent about $6 billion in acquisitions and is seen as the global leader.
Read More
Cancer

Medshine Discovery describes new exportin-1 receptor antagonists for cancer

April 3, 2023
Medshine Discovery Inc. has identified acrylamide compounds acting as exportin-1 (CRM1; XPO1) receptor antagonists reported to be useful for the treatment of cancer.
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Enhanced MRI imaging using Prostatid.

Bot Image’s AI scores an FDA hat trick with clearance to diagnose, detect and monitor prostate cancer

March 28, 2023
By Annette Boyle
The U.S. FDA gave Bot Image Inc. a coveted threefer with 510(k) clearance for its Prostatid artificial intelligence (AI) software for detection, diagnosis and monitoring of prostate cancer using both standard MRI and a non-invasive bi-parametric MRI, which does not require a contrast agent.
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3D illustration showing tumor inside prostate gland and closeup view of cancer cells
Cancer

Discovery and preclinical evaluation of novel PIM-1 kinase inhibitors for prostate cancer

March 28, 2023
Prostate cancer is the second most prevalent solid tumor in men and the fifth leading cause of cancer mortality in men worldwide. One of the proteins overexpressed in prostate cancer is serine/threonine-protein kinase PIM-1. There is evidence about the potential role of PIM-1 as a target in prostate cancer and the effect in cellular apoptosis that reducing levels of PIM-1 through its inducers JAK2/STAT3 may exert.
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Moderna vaccine vial and syringe on tray

Not just Moderna on the HELP hot seat

March 22, 2023
By Mari Serebrov
While Moderna Inc. CEO Stéphane Bancel was the one on the hot seat at a March 22 hearing before the U.S. Senate Health, Education, Labor and Pensions (HELP) Committee, biopharma profitability in general, and capitalism itself, came under fire as committee Chair Bernie Sanders (I-Vt.) railed about corporate greed in the sector.
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Cancer

CSPC Megalith Biopharmaceutical patents new antibody-drug conjugates for cancer

March 21, 2023
CSPC Megalith Biopharmaceutical Co. Ltd. has disclosed antibody-drug conjugates comprising a humanized monoclonal antibody targeting nectin-4 covalently linked to cytotoxic agents through a linker. They are reported to be useful for the treatment of cancer.
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Acer in the hole: Hot flash drug misses in phase IIa

March 17, 2023
By Lee Landenberger
As it struggles to launch a recently approved drug, Acer Therapeutics Inc. hit pause in its ACER-801 (osanetant) program after top-line data in the phase IIa proof-of-concept study failed to hit statistical significance.
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