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BioWorld - Wednesday, April 22, 2026
Home » SARS-CoV-2

Articles Tagged with ''SARS-CoV-2''

Photo of child in bed hugging teddy bear
Inflammatory

COVID-19 and Epstein-Barr cause inflammatory shock in children

March 20, 2025
By Mar de Miguel
Multisystem inflammatory syndrome in children (MIS-C), a serious disorder that develops after SARS-CoV-2 infection, could arise from latent infection of another pathogen, the Epstein-Barr virus (EBV). Researchers at Charité – Universitätsmedizin Berlin and the German Rheumatology Research Center (DRFZ) have linked the inflammatory effect of this co-infection with transforming growth factor β (TGF-β), ruling out the possibility that MIS-C is caused by an autoimmune reaction, or persistence of the coronavirus in the body.
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Disintegrating coronavirus
Infection

3-Deazapurine ribonucleoside shows potent preclinical anti-SARS-CoV-2 activity, preventing pneumonia

March 18, 2025
Although several vaccines and drugs are available against SARS-CoV-2, the search for effective therapeutic agents for COVID-19 and future zoonotic coronaviruses continues. The RNA-dependent RNA polymerase (RdRp) is a relevant drug target in several RNA viral infections, such as SARS-CoV-2 (targeted by the approved drugs remdesivir and molnupiravir), hepatitis C, influenza and dengue viruses.
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Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 18, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
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Coronavirus variants
Infection

ALG-097558 confirmed as an effective pan-coronavirus strategy

March 17, 2025
Although safe and effective vaccines for SARS-CoV-2 have been successfully developed, there are currently no therapeutic approaches available for treating acute infection, particularly for individuals at high risk of severe disease progression, and for preparedness against a potential new coronavirus pandemic.
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Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 14, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
Read More
Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 13, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
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Leyden Labs raises $70M for intranasal flu drugs, acquires Covbio

March 11, 2025
By Marian (YoonJee) Chu
Leyden Laboratories BV added a fresh $70 million in financing to advance Panflu, its phase II-ready intranasal pan-influenza prophylactic medicine, while acquiring Cov Biotechnology Pte. Ltd. (Covbio) and its zoonotic virus-targeting portfolio to prepare for the next pandemic.
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rapid POC TB test
Patents

Researchers develop low-cost, rapid, POC test for TB

March 10, 2025
By Simon Kerton
Professor Alexander Star and researchers from the University of Pittsburgh have filed for protection of their development of a rapid, affordable, and reliable tuberculosis diagnostic tool.
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Other news to note for March 7, 2025

March 7, 2025
Additional early-stage research and drug discovery news in brief, from: Invivyd, Silexion Therapeutics, Sotio Biotech, Vaxxas.
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Infection

University of Arizona describes new PL-pro inhibitors for SARS-CoV-2

March 5, 2025
University of Arizona has identified non-structural protein 3 (nsp3; PL-pro) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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