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BioWorld - Monday, February 2, 2026
Home » SARS-CoV-2

Articles Tagged with ''SARS-CoV-2''

Coronavirus variants
Infection

ALG-097558 confirmed as an effective pan-coronavirus strategy

March 17, 2025
Although safe and effective vaccines for SARS-CoV-2 have been successfully developed, there are currently no therapeutic approaches available for treating acute infection, particularly for individuals at high risk of severe disease progression, and for preparedness against a potential new coronavirus pandemic.
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Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 14, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
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Red coronavirus with long shadow
Infection

Long COVID science is progressing, though therapies have not yet followed

March 13, 2025
By Anette Breindl
In 2020, the Conference on Retroviruses and Opportunistic Infections (CROI) was the first scientific conference to move from in-person to virtual due to the COVID-19 pandemic. On the fifth anniversary of the virtual conference, and the pandemic, some of those earliest COVID-19 patients have still not recovered.
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Leyden Labs raises $70M for intranasal flu drugs, acquires Covbio

March 11, 2025
By Marian (YoonJee) Chu
Leyden Laboratories BV added a fresh $70 million in financing to advance Panflu, its phase II-ready intranasal pan-influenza prophylactic medicine, while acquiring Cov Biotechnology Pte. Ltd. (Covbio) and its zoonotic virus-targeting portfolio to prepare for the next pandemic.
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rapid POC TB test
Patents

Researchers develop low-cost, rapid, POC test for TB

March 10, 2025
By Simon Kerton
Professor Alexander Star and researchers from the University of Pittsburgh have filed for protection of their development of a rapid, affordable, and reliable tuberculosis diagnostic tool.
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Other news to note for March 7, 2025

March 7, 2025
Additional early-stage research and drug discovery news in brief, from: Invivyd, Silexion Therapeutics, Sotio Biotech, Vaxxas.
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Infection

University of Arizona describes new PL-pro inhibitors for SARS-CoV-2

March 5, 2025
University of Arizona has identified non-structural protein 3 (nsp3; PL-pro) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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Novel coronavirus SARS-CoV-2
Infection

KVX-053 alleviates acute lung injury in COVID-19

Feb. 19, 2025
Researchers from Kevirx Inc. and collaborators have described the use of KVX-053, a PTP4A3 inhibitor aimed to be used for the prevention of COVID-19-associated cute lung injury (ALI).
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Infection

Shanghai Curegene Pharmaceutical divulges new Mpro inhibitors

Feb. 4, 2025
Shanghai Curegene Pharmaceutical Co. Ltd. has synthesized 3C-like proteinase (3CLpro; Mpro; nsp5) (SARS-CoV-2; COVID-19 virus) inhibitors reported to be useful for the treatment of SARS-CoV-2 infections (COVID-19).
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Colorized transmission electron micrograph of SARS-CoV-2.
Immune

Ocugen’s OCU-500 inhaled mucosal vaccine for COVID-19 gains IND clearance

Jan. 27, 2025
Ocugen Inc. has received IND clearance from the FDA for OCU-500, an inhaled mucosal vaccine for COVID-19. The National Institute of Allergy and Infectious Diseases (NIAID) will sponsor and conduct a phase I trial of OCU-500 administered via inhalation into the lungs and intranasally as a spray.
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