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BioWorld - Friday, February 6, 2026
Home » G protein-coupled receptors

Articles Tagged with ''G protein-coupled receptors''

American Society of Nephrology

Certa Therapeutics’ FT-011 delivers breakthrough results in inflammatory, fibrotic diseases

Nov. 8, 2022
By Tamra Sami
New research presented by the University of Michigan revealed groundbreaking results for Certa Therapeutics Pty Ltd.’s lead candidate, FT-011, for serious inflammatory and fibrotic diseases.
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American Society of Nephrology

Certa Therapeutics’ FT-011 delivers breakthrough results in inflammatory, fibrotic diseases

Nov. 4, 2022
By Tamra Sami
New research presented by the University of Michigan revealed groundbreaking results for Certa Therapeutics Pty Ltd.’s lead candidate, FT-011, for serious inflammatory and fibrotic diseases. The results of a chronic kidney disease study presented at the American Society of Nephrology meeting on Nov. 4 concluded that FT-011 reverses the activation of molecular markers associated with fibrosis.
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Australian coins and bills

Occurx raises AU$16M to progress lead candidate OCX-063 in chronic kidney disease as it looks for partners

Sep. 13, 2022
By Tamra Sami
Melbourne-based Occurx Pty Ltd. announced a AU$16 million (US$11 million) series B round that will progress lead candidate OCX-063 to phase II trials in chronic kidney disease. The capital raise was jointly led by Brandon Biocatalyst and Uniseed and includes a AU$1.5 million grant from Australian biomedical incubator Cureator.
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Businesswoman pressing dollar sign on touchscreen

Structure Therapeutics nets $33M in financing for GPCR candidates

Aug. 9, 2022
By Doris Yu
Structure Therapeutics Inc. raised $33 million in a financing round to speed up clinical trials of its lead assets targeting chronic diseases and to improve its technology platform. Previously known as Shouti Inc., the company also has rebranded itself as Structure to “reflect its foundation in structural biology and computational design.”
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Businesswoman pressing dollar sign on touchscreen

Structure Therapeutics nets $33M in financing for GPCR candidates

Aug. 5, 2022
By Doris Yu
Structure Therapeutics Inc. raised $33 million in a financing round to speed up clinical trials of its lead assets targeting chronic diseases and to improve its technology platform. Previously known as Shouti Inc., the company also has rebranded itself as Structure to “reflect its foundation in structural biology and computational design.”
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Handshake dollar sign

Back for more: Sosei and Abbvie cut another $1B+ deal

Aug. 2, 2022
By Lee Landenberger
Sosei Heptares and Abbvie Inc. have built on the huge, multitarget deal they cut a little more than two years ago by signing another one.
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Gold dollar sign

Septerna’s $100M series A will target GPCR development

Jan. 27, 2022
By Lee Landenberger
The G protein-coupled receptor (GPCR) is a foundational building block of modern medicine. While nearly everyone has taken one sometime in the past few decades, development has greatly slowed. With a fundraiser in hand, Septerna Inc. is looking at new ways of working around and through old problems.
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Oral medication

Shouti raises $100M in series B round to turn injectable medicines into pills

Oct. 29, 2021
By Doris Yu and David Ho
Shouti Inc. raised $100 million in a series B round led by BVF Partners LP to advance its discovery platform for designing oral medicines and to speed up the development of its candidates. The Shanghai and California-based company has secured a total of $158 million in funding so far.
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Tape measure wrapped around feet on scale

Exome study identifies new genetic influences on weight

July 2, 2021
By Anette Breindl
An exome sequencing study of more than 600,000 individuals of European and mixed American ancestry has identified more than a dozen genes, including five brain-expressed G protein-coupled receptors, that were associated with body mass index.
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Gold coins and sprouting plants

Formed by former Novartis CEO, Aditum Bio fund looks to target treatment gaps

Nov. 2, 2020
By Nuala Moran
LONDON – Former CEO of Novartis AG Joe Jimenez is emerging back into the limelight as founder and managing director of Aditum Bio, a new $135 million venture capital fund set up to create five to six companies to take forward early stage compounds in-licensed from pharma.
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