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Year in Review: Promise of genomics finally impacting clinical care

December 30, 2019

LONDON – Twenty years on from sequencing of the first draft of the human genome and the associated hype, 2019 was the year that the science of genomics truly began to make an impact in health care.

The art of war

By spying on quorum sensing, immune system picks its battles

December 30, 2019

By Anette Breindl

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In the Dec. 20, 2019, issue of Science, Stefan Kaufmann, who is the founding director of the Max Planck Institute for Infection Biology, and his colleagues report that the immune system could calibrate its response to Pseudomonas aeruginosa by monitoring the bacterial quorum sensing chatter.

Bioworld MedTech’s Cardiology Extra for Dec. 30, 2019

December 30, 2019

By Liz Hollis

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Keeping you up to date on recent developments in cardiology.

Bioworld MedTech’s Neurology Extra for Dec. 27, 2019

December 27, 2019

By Andrea Applegate and Anette Breindl

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Keeping you up to date on recent developments in neurology.

Breaching all three meninges improves drug delivery to brain

December 27, 2019

By Anette Breindl

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A single injection of SOD1-targeting RNA into the subpial space, which is below the innermost meningeal layer, was able to spread throughout the spinal cord and, via retrograde delivery, into brain centers that project to the spinal cord in several animal models, including primates.

The art of war?

By spying on quorum sensing, immune system picks its battles?

December 27, 2019

By Anette Breindl

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“Bacteria often only do harm at certain concentrations,” Stefan Kaufmann told BioWorld. In fact, bacteria have evolved an entire communication system, so-called quorum sensing, to monitor how many of their colleagues are in the vicinity, and then switch from growth to virulence only at high densities.?

Bench Press for Dec. 27, 2019

December 27, 2019

By Anette Breindl

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Scientists at the University of Tuebingen have identified a network of antifibrotic RNAs, and showed that this network was controlled by the transcription factor Pparg. Fibrosis, which is essentially the formation of inappropriate scar tissue, contributes to multiple diseases, and its molecular mechanisms are poorly understood.

Bioworld MedTech’s Oncology Extra for Dec. 24, 2019

December 24, 2019

By Mark McCarty and Anette Breindl

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Keeping you up to date on recent developments in oncology.

Spot on

Breaching all three meninges improves drug delivery to brain

December 24, 2019

By Anette Breindl

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APOE has secrets left

Large datasets, good statistics allow disease-agnostic SNP discoveries

December 24, 2019

By Nuala Moran

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LONDON – While large-scale biobanks that link genomics to longitudinal health records of diagnosis, treatment and outcomes promise to revolutionize the understanding of the genetics of complex disease, the detailed statistical analysis of those high-dimensional data is still very much in its infancy.

Gilead’s remdesivir enters China phase III trial to fight coronavirus
BioWorld
BEIJING – China will kickstart a phase III trial Feb. 3 to determine whether patients with 2019-nCoV can be treated with Gilead Sciences Inc.’s NUC inhibitor,...
Coronavirus: Chinese researchers claim TCM herbal remedy could ‘inhibit’ 2019-nCoV
BioWorld
HONG KONG – In another example that communication is proving as difficult as containment in the current coronavirus outbreak, China’s state media reported, to...
Hong Kong researchers create fastest coronavirus diagnostic test to date
BioWorld
HONG KONG – A team of researchers at Hong Kong University of Science and Technology (HKUST) claim to have invented the world’s fastest portable 2019-nCoV...
Researchers trace COVID-19’s family tree to battle outbreak and ‘infodemic’
BioWorld
SEATTLE – Tracing the family tree of COVID-19 through its evolving DNA sequence makes it possible to disprove many false claims circulating on social media about...
In China, the race is on to develop, approve test kits for coronavirus
BioWorld MedTech
BEIJING – Chinese regulators are speeding up to approve more test kits for the deadly coronavirus that already has killed 170 people and infected more than 7,700...

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