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BioWorld MedTech’s Orthopedics Extra for July 29, 2020

July 29, 2020
Keeping you up to date on recent developments in orthopedics, including: Lego-inspired bone and soft tissue repair with tiny, 3D-printed bricks; Mutant zebrafish reveals a turning point in spine's evolution; Newly discovered cells act as a warning signal for rheumatoid arthritis flares.
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ENCODE project illustration
Phase IV now underway

Data reported from ENCODE phase III

July 29, 2020
By Anette Breindl
Researchers from the Encyclopedia of DNA Elements (ENCODE) consortium reported data from the third phase of the project. Phase III data, which were published in more than a dozen papers in Nature and its sister journals on July 29, 2020, consisted of 6,000 experiments performed on around 1,300 samples.
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Silhouette with keyhole

Alzheimer’s blood test could improve trials, help find treatments

July 28, 2020
By Anette Breindl
CYBERSPACE – Data presented at the virtual 2020 Alzheimer's Association International Conference (AAIC) and reported in the July 28, 2020, online issue of the Journal of the American Medical Association (JAMA) demonstrated that blood levels of phosphorylated tau-217 (Ptau-217) did as well as cerebrospinal (CSF)- and PET-based biomarkers, and significantly better than other blood-based biomarkers, at discriminating individuals with Alzheimer’s disease (AD) from those with other neurodegenerative disorders.
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BioWorld MedTech’s Oncology Extra for July 28, 2020

July 28, 2020
By Mark McCarty
Keeping you up to date on recent developments in oncology, including: ctDNA associated with poor outcomes in triple-negative breast cancer; Protons beat IMRT for locally advanced esophageal cancer; Study affirms cancer patients avoiding clinical care.
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BioWorld MedTech’s Cardiology Extra for July 27, 2020

July 27, 2020
By Liz Hollis
Keeping you up to date on recent developments in cardiology, including: Genetic testing for heart diseases could help identify risks; New option for monitoring heart health; Scorpions eyed for heart attacks.
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Electrical activity of the brain
EEGs and endotypes

From cells to cortices, ways to improve neurological disease classification

July 24, 2020
By Anette Breindl
Cancer treatment has been transformed, at its root, by a transformational change in how it is classified. Those successes have not escaped the notice of researchers in other areas of biomedicine, and diseases including heart failure, asthma and polycystic ovarian syndrome are being looked at with an eye to subdividing them in ways that brings diagnostics into the molecular era.
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BioWorld MedTech’s Neurology Extra for July 24, 2020

July 24, 2020
By Andrea Applegate
Keeping you up to date on recent developments in neurology, including: Novel drug delivery particles use neurotransmitters as a 'passport' into the brain; SARS-CoV-2 infection of non-neuronal cells, not neurons, may drive loss of smell in patients with COVID-19; Pandemic to accelerate adoption of electronic patient portal for epilepsy.
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Normal vision vs. vision with AMD

Bench Press for July 24, 2020

July 24, 2020
By Anette Breindl
BioWorld looks at translational medicine, including: Structural study gives insight into plaque formation; Studying labor identifies new pain mechanism; AHR inhibition suppresses Zika infection; iPSCs find best therapy for Best disease.
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BioWorld MedTech’s Diagnostics Extra for July 23, 2020

July 23, 2020
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Scaling patient stratification in EHRs using deep learning; Improving prognosis of pancreatic cancer; Mitochondria, interneurons, cognition link explored.
Read More
Electrical activity of the brain
EEGs and endotypes

From cells to cortices, ways to improve neurological disease classification

July 23, 2020
By Anette Breindl
Cancer treatment has been transformed, at its root, by a transformational change in how it is classified. These days, which organ a tumor arises in is often less important than its molecular drivers, which can be sensitive either to specific targeted treatments, or increase the chance that a tumor will respond to immunotherapy. Those successes have not escaped the notice of researchers in other areas of biomedicine, and diseases including heart failure, asthma and polycystic ovarian syndrome are being looked at with an eye to subdividing them in ways that brings diagnostics into the molecular era. Nowhere do those changes have greater potential than in disorders of the brain – in part because there is nowhere much to go but up as far as classifying neurological diseases goes.
Read More
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