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Fallopian tubes, ovaries and uterus

Ovarian fibrosis-mediated ovulation failure is reversible: study

June 21, 2022
By Subhasree Nag
Failure to ovulate and release mature oocytes is one of the most common female infertility problems. With increasing age or conditions like obesity, no oocytes are released even on ovulation induction with hormonal treatment.
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3D illustration of heart cross section

Cytokine promotes heart repair after infarct

June 20, 2022
By Anette Breindl
Researchers at Hannover Medical School have gained new insights into the cytokine meteorin-like (METRNL) and its role in promoting heart repair after myocardial infarction.
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Hands holding test tubes at laptop

Combinatorial analytics identifies hundreds of precise drug repositioning opportunities

June 17, 2022
By Patrick Cole
It is well known that the development of a new drug is exorbitantly expensive and is a process which usually fails. Researchers at PrecisionLife posit that failure and the many patients with unmet treatment needs result from an over simplistic view of disease pathogeneses and an overreliance on a narrow range of target genes and pathways.
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Eye wireframe illustration

Blood vessel shape predicts what shape the heart is in

June 16, 2022
By Anette Breindl
The eyes may be the window to the heart as well as the soul – particularly, to whether that heart is at risk of an infarct, researchers reported last week at the annual congress of the European Society of Human Genetics.
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Digital heart illustration

Scientists discover new mechanism that causes cardiac hypertrophy in response to pressure overload

June 15, 2022
New treatments for cardiac hypertrophy, a thickening of the heart in response to pressure overload, could potentially treat or even reverse the condition after a new breakthrough discovery identified the mechanism that causes the heart's muscle to thicken, increasing the risk of irregular heart rhythms and heart failure.
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Sickle cells

EHA 2022 presentations describe sickle cell disease headway and headwinds

June 14, 2022
By Anette Breindl and Patrick Cole
At the European Hematology Association's annual meeting in Vienna last week, companies reported impressive progress for the treatment of sickle cell disease.
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Sickle cell disease

At EHA 2022, sickle cell disease headway and headwinds

June 13, 2022
By Anette Breindl
At the European Hematology Association’s annual meeting in Vienna last week, companies reported impressive progress for the treatment of sickle cell disease.
Read More
Lab sample and bone marrow illustration

At EHA 2022, insights into multiple reasons for marrow failure

June 13, 2022
By Anette Breindl
At the 2022 Annual Congress of the European Hematology Association, researchers from the Spanish National Cancer Institute reported how high levels of the RNA-binding protein hnRNP-K could lead to bone marrow failure.
Read More
Parkinson's disease illustration showing neurons containing alpha-synuclein

Circuit, synuclein insights reported in Parkinson's disease

June 10, 2022
By Anette Breindl
A Massachusetts Institute of Technology-led team has identified distinct midbrain circuits that contributed to both motor and psychiatric symptoms of Parkinson's disease in animal models. Activating the circuits could reverse both types of symptoms.
Read More
Illustration of DNA, magnifying glass

For mutations, "synonymous" is not a synonym for silent, study finds

June 9, 2022
By Anette Breindl
A central assumption about so-called synonymous mutations, which are changes in the coding sequence of proteins that do not lead to changes in its amino acid sequence, is being questioned by a study published in the June 8, 2022, issue of Nature.
Read More
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