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BioWorld - Thursday, June 1, 2023
Home » Topics » Science

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Neurons

Neurotrophic signaling deficiency exacerbates Alzheimer's risk factors

June 28, 2021
By John Fox
No Comments
A deficiency in neurotrophic factor signaling has been shown to exacerbate environmental risk factors for the development of Alzheimer's disease pathogenesis in mice, according to a study reported in the June 22, 2021, online edition of the Proceedings of the National Academy of Sciences.
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Tiny 3D-printed bioscaffold on gloved finger

Australian researchers outsmart 3D printers by printing biomaterials in empty space

June 25, 2021
By Tamra Sami
No Comments
PERTH, Australia – Researchers at RMIT University and St. Vincent's Hospital in Melbourne have flipped traditional 3D printing to create more intricate biomedical structures, advancing new technologies for regrowing bones and tissue. Instead of making the bioscaffolds directly, the team 3D printed molds with intricately patterned cavities and then filled them with biocompatible materials, before dissolving the molds away.
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Stem cells

Back to the basics for new insights, with new technology

June 25, 2021
By Anette Breindl
No Comments
Sometimes, scientific progress comes from conceptual insights that arrive in a flash. More often, however, such progress arrives in a decidedly less glamorous, though no less important, manner – through the development of new technologies in what can be a very slow iterative cycle of getting a new method to work.
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PolyU's biomimetic nanosheet (right), FePSe3 powder (left)

PolyU develops biomimetic nanosheet for cancer therapy and imaging

June 22, 2021
By Elise Mak
No Comments
Researchers from The Hong Kong Polytechnic University said they have used two-dimensional nanosheets to develop a biomimetic nanosheet that can monitor tumor development, treat tumors and monitor the treatment progress in real-time.
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Arthritis pain illustration

STING inhibitors target inflammatory diseases

June 22, 2021
No Comments
A China-U.S. study led by scientists at China Pharmaceutical University (CPU) and Harvard University has identified a new small-molecule antagonist of the stimulator of interferon genes (STING) signaling pathway, SN-011, and shown it to be safe, effective and specific in STING-driven inflammatory diseases.
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Fallopian tubes, ovaries and uterus

Period piece: endometrial organoids from menstrual blood

June 21, 2021
By Nuala Moran
No Comments
PolyU's biomimetic nanosheet (right), FePSe3 powder (left)

PolyU develops biomimetic nanosheet for cancer therapy and imaging

June 18, 2021
By Elise Mak
No Comments
Researchers from The Hong Kong Polytechnic University (PolyU) said they have used two-dimensional nanosheets (FePSe3) to develop a biomimetic nanosheet that can monitor tumor development, treat tumors and monitor the treatment progress in real-time. With positive results from mice, the team hopes to further test it on larger animals, then move on to clinical studies.
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Herpes simplex virus

HSV-targeting compound affects latent infection

June 18, 2021
By Anette Breindl
No Comments
A German-American team of researchers has developed a compound that could affect latent herpes simplex virus (HSV) infections, reducing the risk of recurrence even after an infection had fully established itself in its neuronal reservoir.
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Acetaminophen pills

Tylenol could find role in gene therapy

June 17, 2021
By Anette Breindl
No Comments
Researchers at Oregon Health & Science University have turned acetaminophen's toxicity into an asset, using it to select genetically modified hepatocytes in vivo.
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Cancer cells

Switching on prodrugs with radiotherapy shows promise

June 17, 2021
By John Fox
No Comments
Local tumor conversion of a prodrug to an active agent using clinically relevant radiotherapy may herald a new era in targeted and directed cancer chemotherapy.
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