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Heart and lungs

Heartpoint Global sees success with heart implant system in animal studies

Aug. 2, 2022
By David Ho
Heartpoint Global Inc. has reached a milestone in the ongoing preclinical trials of its Heartpoint Global Implant System (HPGS), focused on treating left heart diseases, congestive heart failure, and structural pulmonary hypertension. In large animal studies, the system appeared to significantly improve the structure of the heart and the function of the heart-lung system.
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Map illustrating origin and spread of coronavirus

New analyses conclude that lab origin of SARS-CoV-2 is ‘extremely unlikely’

Aug. 2, 2022
By Nuala Moran
The controversy about the origins of the SARS-CoV-2 virus and the accusations that it escaped from the Wuhan Institute of Virology, or even that it was deliberately engineered there, could – possibly – be brought to a close by two papers published July 26, 2022.
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Coronavirus spike protein

Targeting S2 could lead to broad coronavirus protection

Aug. 2, 2022
By Nuala Moran
Since the very beginning of the COVID-19 pandemic, in addition to the attempts to rapidly develop a vaccine that was effective against current strains, researchers have been looking for a vaccine that could protect more broadly against multiple coronaviruses. 
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Woman and 3D brain

Brain hypermutability is a process associated with aging

Aug. 1, 2022
By Mar de Miguel
Sequence analysis of 131 human brains has revealed the mutagenesis processes that take place throughout life, from development to senescence. In a new study published in the July 29, 2022, issue of Science, the authors described how high rates of brain somatic mutations (what they call hypermutability) correlated with age.
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3D model of a protein molecule

‘3D view of the protein universe’ as Deepmind reveals 200M protein structures

July 29, 2022
By Nuala Moran
It is now possible to look up the 3D structure of every known protein following the latest release of Alphafold, an open database run in partnership by Deepmind, the London-based artificial intelligence company owned by Google parent Alphabet and the European Molecular Biology Laboratory’s European Bioinformatics Institute in Cambridge, U.K.
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Professor Hugh Watkins, lead investigator at Cureheart

Scientists to test whether base editing could cure killer heart diseases

July 29, 2022
By Richard Staines
Scientists will investigate whether cutting-edge technology such as base editing could be used to cure inherited heart muscle conditions after an international team co-led by Harvard Medical School won a research challenge. The $36 million Big Beat Challenge, run by the British Heart Foundation, is one of the largest non-commercial awards ever given and will focus on inherited heart muscle diseases known as genetic cardiomyopathies.
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Person holding stomach in pain

Gut bug-produced histamine worsens abdominal pain in irritable bowel syndrome

July 29, 2022
By Mar de Miguel
According to a new study published in the July 27, 2022, issue of Science Translational Medicine, a lower intake of fermentable carbohydrates produces changes in the intestinal microbiota that decrease histamine production reducing chronic abdominal pain in patients with irritable bowel syndrome.
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Coronavirus spike protein

Targeting S2 could lead to broad coronavirus protection

July 29, 2022
By Nuala Moran
Since the very beginning of the COVID-19 pandemic, in addition to the attempts to rapidly develop a vaccine that was effective against current strains, researchers have been looking for a vaccine that could protect more broadly against multiple coronaviruses. That has prompted attempts to harness the potential of the more conserved S2 subunit of the spike protein via which SARS-CoV-2 enters human host cells.
Read More
Brain cancer illustration

Neuron-like cells are glioblastoma's evil mastermind

July 28, 2022
By Anette Breindl
Tumor heterogeneity is recognized as an important way in which tumors are able to grow, invade surrounding tissue, metastasize and develop resistance to therapies. But linking specific states to the overall biology of tumors has been a challenge.
Read More
Map illustrating origin and spread of coronavirus

New analyses conclude that lab origin of SARS-CoV-2 is ‘extremely unlikely’

July 27, 2022
By Nuala Moran
The controversy about the origins of the SARS-CoV-2 virus and the accusations that it escaped from the Wuhan Institute of Virology, or even that it was deliberately engineered there, could – possibly – be brought to a close by two papers published July 26, 2022.
Read More
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