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BioWorld - Sunday, April 5, 2026
Home » Topics » Science

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Preclinical through phase III, new COVID-19 therapy trials ramp up

April 30, 2021
By Michael Fitzhugh and Anette Breindl
Urgency to meet the world's worsening load of COVID-19 cases appeared unflagging Thursday, with four new trials kicking off to evaluate treatments aimed at keeping people from progressing to worsened disease and reports on two new variant-focused efforts yielding signs of preclinical promise.
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BioWorld MedTech’s Diagnostics Extra for April 29, 2021

April 29, 2021
By Meg Bryant and Anette Breindl
Keeping you up to date on recent developments in diagnostics, including: Urine test could reduce prostate cancer biopsies; Neurons forget who they are in Alzheimer’s disease; Sensor can predict hallucinogenic serotonin receptor effects.
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Liver illustration

Fat no proxy for quality in transplant livers

April 29, 2021
By Anette Breindl
Researchers have gained new insights into what makes for transplantable livers – and what doesn’t. In a clinical trial of 12 livers, a team from Massachusetts General Hospital showed that both livers with high fat content and those without could be viable for transplantation.
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Melissa Davis, Weill Cornell Medical Center

No quick fixes, but opportunities exist for dismantling disparities in science

April 28, 2021
By Anette Breindl
Twenty years after the first, exclusively white human genomes were fully sequenced, science finds itself in the same position as the rest of society: with the uncomfortable realization that old inequalities are often morphing, rather than disappearing. Vocal racists – scientists of the stripe of a James Watson – are by no means a thing of the past. But they are only the tip of the iceberg.
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BioWorld MedTech’s Orthopedics Extra for April 28, 2021

April 28, 2021
By Holland Johnson
Keeping you up to date on recent developments in orthopedics, including: Skin and bones repaired by bioprinting during surgery; Researchers use AI to detect wrist fractures; Smart Score quantifies clinical outcomes for shoulder arthroplasty patients.
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Chromosomes
Bench Press

X chromosome reactivation widely affects proteome

April 28, 2021
By Anette Breindl
BioWorld looks at translational medicine, including: Neurons forget who they are in Alzheimer’s disease; Sensor can predict hallucinogenic serotonin receptor effects.
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Stroke illustration: brain, artery, neurons

Cell death finding may improve stroke management

April 28, 2021
By John Fox
Under certain circumstances, a normally innocuous key molecular intermediate of regular cell metabolism, farnesyl pyrophosphate, can trigger neuronal lysis and cell death, according to a study led by Chinese researchers at Tsinghua and Peking universities in Beijing.
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Mosquito

Collaboration promotes new antimalarial drug development

April 27, 2021
By John Fox
A collaboration aimed at identifying and developing potential new antimalarial drug candidate drugs has been announced between Walter and Eliza Hall Institute for Medical Research in Melbourne, Australia, and Janssen Pharmaceutica, with assistance from Johnson & Johnson Innovation.
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BioWorld MedTech’s Oncology Extra for April 27, 2021

April 27, 2021
By Mark McCarty and Anette Breindl
Keeping you up to date on recent developments in oncology, including: New test lends insight into aggressiveness of prostate cancer, could reduce biopsy; Loss of cell polarity is lung cancer precursor; A different path to specificity for Ras inhibitors; Thin films for detection, calibration of proton beams.
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PET imaging

ICAM-1 orchestrates radiotherapy abscopal effect

April 26, 2021
By John Fox
A study led by Chinese radiologists at Peking University in Beijing has shown that positron emission tomography imaging of intercellular adhesion molecule-1 (ICAM-1) expression is a predictor for the abscopal effect, whereby nonirradiated cancers respond to radiotherapy.
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