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BioWorld - Wednesday, December 10, 2025
Home » Topics » Science » Drug resistance

Drug resistance
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Bacteria in petri dishes

Glutamine promotes antibiotic uptake to kill MDR bacteria

Dec. 30, 2021
By John Fox
Combining the metabolites glutamine or inosine with ampicillin (AMP) could represent a new therapeutic approach to antimicrobial resistance that also avoids the development of acquired resistance to next-generation antibiotics, according to a new Chinese study led by scientists at Sun Yat-sen University (SYSU) in Guangzhou.
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Biocytogen forms partnership and closes new financing round

July 20, 2021
By Doris Yu
Having created a profitable preclinical services business, Biocytogen Pharmaceuticals Co. Ltd. is now working to develop its own pipeline of antibody therapeutics, recently inking a partnership with China Resources Biopharmaceutical Co. Ltd. to develop drugs for oncology and immunology indications and raising “tens of millions of dollars” in a new financing round to support the development of its antibody drugs.
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Biocytogen forms partnership and closes new financing round

July 16, 2021
By Doris Yu
Having created a profitable preclinical services business, Biocytogen Pharmaceuticals Co. Ltd. is now working to develop its own pipeline of antibody therapeutics, recently inking a partnership with China Resources Biopharmaceutical Co. Ltd to develop drugs for oncology and immunology indications and raising “tens of millions of dollars” in a new financing round to support the development of its antibody drugs.
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Ovarian cancer illustration

Beigene’s PARP inhibitor approved for recurrent ovarian cancer in China

May 11, 2021
By Elise Mak
Beigene Ltd.’s PARP inhibitor, pamiparib, won conditional approval from China’s National Medical Products Administration for treating patients with germline BRCA mutation-associated recurrent advanced ovarian, fallopian tube or primary peritoneal cancer who have been treated with two or more lines of chemotherapy.
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Ovarian cancer illustration

Beigene’s PARP inhibitor approved for recurrent ovarian cancer in China

May 7, 2021
By Elise Mak
Beigene Ltd.’s PARP inhibitor, pamiparib, won conditional approval from China’s National Medical Products Administration for treating patients with germline BRCA mutation-associated recurrent advanced ovarian, fallopian tube or primary peritoneal cancer who have been treated with two or more lines of chemotherapy.
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RNA virus illustration
Newco news

Covicept lands Forbion backing for mission to tackle RNA viruses

Feb. 5, 2021
By Michael Fitzhugh
Covicept Therapeutics Inc., a young San Diego-based company focused on developing a small molecule to inhibit the replication and spread of SARS-CoV-2 and other RNA viruses, has launched with $2.3 million in seed funding from European VC firm Forbion. The company, spun out of research at the University of California, San Diego, aims to initiate its first clinical study in the middle of 2021.
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Blood cells and bacteria

Antimicrobial polymers AMP up fight against MDR bacteria

Dec. 4, 2020
By John Fox
An international study led by Nanyang Technological University in Singapore has designed and synthesized broad-spectrum antimicrobial polymers (AMPs) and demonstrated the safety and efficacy of two such agents against multidrug-resistant (MDR) bacteria in mouse models of sepsis.
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Blood cells and bacteria

Antimicrobial polymers AMP up fight against MDR bacteria

Dec. 1, 2020
By John Fox
An international study led by Nanyang Technological University in Singapore has designed and synthesized broad-spectrum antimicrobial polymers (AMPs) and demonstrated the safety and efficacy of two such agents against multidrug-resistant (MDR) bacteria in mouse models of sepsis.
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Blood cells and bacteria

Antimicrobial polymers AMP up fight against MDR bacteria

Nov. 25, 2020
By John Fox
An international study led by Nanyang Technological University in Singapore has designed and synthesized broad-spectrum antimicrobial polymers (AMPs) and demonstrated the safety and efficacy of two such agents against multidrug-resistant (MDR) bacteria in mouse models of sepsis.
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Enterobacteriaceae

Neuro-drug repurposed to treat MDR gram-negative sepsis

Nov. 19, 2020
By John Fox
A study by Australian microbiologists at Queensland, Melbourne and Griffiths universities has shown that the candidate neurodegenerative disease drug PBT-2, combined with a polymyxin antibiotic, induced potent antimicrobial activity against polymyxin-resistant gram-negative pathogens.
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