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Home » Topics » Science » Vaccines

Vaccines
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microfluidic patch pump
Patents

Researchers file patent for microfluidic patch-pump drug delivery platform

June 12, 2025
By Simon Kerton
Researchers from Virginia Polytechnic Institute and State University filed for protection of their development of a slim, painless, and affordable microfluidic infusion pump device for the continuous transdermal delivery of drugs.
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Illustration of human papillomavirus (HPV) infection
Infection

mRNA vaccine could prevent and treat HPV-related cancer

April 3, 2024
A group of scientists at Shanghai Virogin Biotech Co. and Zhujiang Hospital in China designed a new mRNA vaccine that could prevent tumor formation associated with human papillomavirus 16 (HPV16) and also reduce its size if used as a treatment.
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Infection

PIV5-vectored OspA-based vaccine provides long-term protection against B. burgdorferi infection in mice

Feb. 21, 2024
Immuno Technologies Inc. and affiliated organizations have published preclinical data on a novel parainfluenza virus 5 (PIV5)-vectored intranasal vaccine for Lyme disease.
Read More
Vaccine vial and syringe
Infection

Evaxion Biotech and MSD complete initial phases of bacterial vaccine collaboration

Feb. 21, 2024
Using its proprietary AI-Immunology platform, Evaxion has identified novel vaccine targets against a bacterial pathogen causing severe health issues.
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Colorized scanning electron micrograph of mpox virus (red) on the surface of infected VERO E6 cells (green).
Infection

Multivalent mRNA vaccine prevents mpox disease

Feb. 16, 2024
By Mar de Miguel
A vaccine based on messenger RNA (mRNA) technology against four surface proteins of the envelope and the inner membrane of the mpox virus (MPXV) demonstrated its efficacy in two animal models. Biontech SE scientists designed and tested two different combinations of antigens in mice and macaques for the two infective forms of the virus. One of them showed better results for its evaluation in clinical trials preventing the disease.
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vaxess vaxxine patch
Patents

Vaxess device improves application of vaccine patches

Jan. 9, 2024
By Simon Kerton
Vaxess Technologies Inc. seeks patent protection for devices that enable the reliable application of silk fibroin-based microneedle medicament patches used for delivering small molecule drugs, vaccines, peptides, biologics, antibodies, hormones or other materials into or through the skin.
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Coronavirus, mRNA and syringe
Infection

Off-target immune response from modified mRNA impacts future development

Dec. 7, 2023
By Nuala Moran
The Nobel Prize-winning modification that prevents the innate immune system from recognizing injected mRNA as foreign and blocking transcription of the protein it encodes has been found on some occasions to cause ribosomal frameshifting.
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Coronavirus, mRNA and syringe

Off-target immune response from modified mRNA impacts future development

Dec. 6, 2023
By Nuala Moran
The Nobel Prize-winning modification that prevents the innate immune system from recognizing injected mRNA as foreign and blocking transcription of the protein it encodes has been found on some occasions to cause ribosomal frameshifting.
Read More
Cervical cancer cell
Immuno-oncology

Lenti-HPV-07 vaccine achieves complete HPV-induced tumor eradication in the preclinical setting

Sep. 28, 2023
Among all human papillomavirus (HPV) types described so far, the two most abundant – HPV16 and HPV18 – are responsible for 71% of all cervical cancers. The vaccines currently used are effective in preventing viral infection, but have no effect on already infected or maligned cells.
Read More
Close-up photo of multi-colored beads threaded onto a string
Immune

Double-double-duty EBV vaccine shows promise in animal models

Aug. 9, 2023
By Anette Breindl
An experimental vaccine that contained antigens of both lytic and latent phases of Epstein-Barr virus (EBV), and induced both an antibody and a T cells response, was able to generate broad and long-lasting immunity against EBV in mouse models of infection. Researchers from the QIMR Berghofer Medical Research Institute and Elicio Therapeutics Inc. reported those results online in Nature Communications on Aug. 8, 2023.

For some viruses, the challenge to developing a vaccine is their rapid mutation rate. This is the major challenge to developing an HIV vaccine or a universal flu vaccine. EBV is different. Its superpower is its ability to hide.
Read More
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