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BioWorld - Friday, December 26, 2025
Home » Topics » Clinical

Clinical
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4-10-Diabeloop.png

Eyeing FDA clearance, Diabeloop kicks off real-world study

April 10, 2020
By Bernard Banga
PARIS – Diabeloop SAS, of Grenoble, France, has launched a real-world study of its automated insulin delivery DBLG1 system, incorporating the Dana-I pump from Sooil Development Co. Ltd., of Seoul, South Korea.
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Stomach and intestine

Standing out from its Pieris, gastric player could win with liver-tox lack

April 10, 2020
By Randy Osborne
Boston-based Pieris Pharmaceuticals Inc., during its March 12 earnings call, talked up gastric cancer prospect PRS-343, a 4-1BB/HER2 bispecific for HER2-positive solid tumors, which has turned up single-agent and checkpoint-combination antitumor activity.
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In the clinic for April 10, 2020

April 10, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Company List: Astrazeneca, Biocryst, Cyclerion.
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Australia’s Kazia reports strong overall survival benefit in phase II glioblastoma trial; raises AU$7.2M

April 9, 2020
By Tamra Sami
PERTH, Australia – Sydney-based Kazia Therapeutics Ltd. reported interim data showing that lead candidate paxalisib (formerly GDC-0084) saw a positive overall survival signal in its phase II glioblastoma trial, and the company raised AU$7.2 million (US$4.4 million) days after the data were released.
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In the clinic for April 9, 2020

April 9, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Aridis, Bridge, Firstwave, Fujifilm, Kezar, Laurent, Mesoblast, Neoimmunetech, Otonomy, Sirnaomics, Tenax, Vigeo, Zelira.
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Drug vial and syringe
Toward breathing easier

Novavax coronavirus vaccine, Bellerophon COVID-19 therapy near phase I

April 8, 2020
By Michael Fitzhugh
Novavax Inc., one of the first biopharma companies to reveal its efforts to develop a SARS-CoV-2 vaccine in January, has identified a prefusion protein for testing in an Australian phase I trial, slated to start in mid-May.
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In the clinic for April 8, 2020

April 8, 2020
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Addex, Aivita, Catalyst, Neuclone, Novotech, Obi, Trillium, Viriom.
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Blood cells and bacteria

Sepsis study may yield new treatment strategies

April 7, 2020
By John Fox
Indian scientists have discovered a previously unknown mechanism underlying life-threatening sepsis and proposed a new treatment strategy centered upon cell-free chromatin (cfCh), they reported in the March 4, 2020, edition of PLOS ONE.
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Magventure-TMS.png

High-dose TMS offers depression remission in small Stanford study

April 7, 2020
By Stacy Lawrence
To better tap into the potential of transcranial magnetic stimulation (TMS), Stanford University researchers developed a high-dose, precision-targeted protocol known as Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT).
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Coronavirus, lungs

MSC-based therapies from Mesoblast, Cynata advance to tackle COVID-19 ARDS

April 7, 2020
By Tamra Sami
PERTH, Australia – Australian stem cell therapy company Mesoblast Ltd. announced that the FDA gave it the green light to test its allogeneic mesenchymal stem cell (MSC) product candidate remestemcel-L in patients with acute respiratory distress syndrome (ARDS) caused by coronavirus (COVID-19). “We’re going to be evaluating whether an injection of our cells intravenously can tone down the immune system just enough so it gets rid of the virus but doesn’t destroy your lungs at the same time,” Mesoblast CEO Silviu Itescu told BioWorld.
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