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BioWorld - Friday, December 19, 2025
Home » Topics » Deals and M&A, BioWorld Science

Deals and M&A, BioWorld Science
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Microscope with beakers and flasks
Drug design, drug delivery & technologies

Tevogen Bio expands Microsoft AI-powered collaboration

Jan. 27, 2025
Tevogen Bio Holdings Inc. has expanded its relationship with Microsoft Corp. to broaden their AI-focused collaboration and build its Predictcell technology for predictive precision T-cell targeting.
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3D illustration of human digestive system

More China ADCs: Arrivent gets GI cancer drug in $1.2B Lepu deal

Jan. 23, 2025
By Marian (YoonJee) Chu
A year after its $175 million IPO in 2024, Arrivent Biopharma Inc. picked up rights to develop and commercialize Lepu Biopharma Co. Ltd.’s antibody-drug conjugate (ADC) candidate, MRG-007, worldwide excluding the greater China region.
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Scientist, microscope and dropper
Hematologic

Immvention, Novo Nordisk collaborate on BACH1 inhibitors

Jan. 23, 2025
Immvention Therapeutix Inc. has entered into a collaboration and license agreement with Novo Nordisk A/S to co-develop oral therapies for sickle cell disease and other chronic conditions.
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Floating antibody drug conjugates
Immuno-oncology

Arrivent Biopharma licenses ex-China rights to Lepu’s ADC for gastrointestinal cancers

Jan. 22, 2025
Arrivent Biopharma Inc. has entered into an exclusive license agreement with Lepu Biopharma Co. Ltd. for MRG-007, an antibody-drug conjugate (ADC) in development for gastrointestinal cancers.
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3D illustration of a nerve cell
Neurology/psychiatric

Kyorin signs option agreement for Biodol’s BDT-272 for pain

Jan. 15, 2025
Kyorin Pharmaceutical Co. Ltd. has entered into an option agreement with Biodol Therapeutics SAS.
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Molecules and RNA enclosed by a lipid bilayer
Hematologic

Orna, Vertex next-gen sickle cell, thalassemia deal could reach $4.3B+

Jan. 8, 2025
By Karen Carey
About four years after launch, Orna Therapeutics Inc. signed its second major deal, this time validating the lipid nanoparticle delivery technology it acquired through its Renagade Therapeutics Inc. buyout in May 2024, with Vertex Pharmaceuticals Inc. seeking next-generation approaches for hemoglobinopathies.
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Illustration of myocytes
Endocrine/metabolic

Ibio licenses long-acting anti-myostatin antibody from Astralbio

Jan. 7, 2025
Ibio Inc. has expanded its cardiometabolic and obesity treatment development program by in-licensing a long-acting anti-myostatin antibody from Astralbio Inc. The antibody, now named IBIO-600, was identified by Astralbio using Ibio’s proprietary technology stack.
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Connecting puzzle pieces
Inflammatory

STAT6 stat sig? Kaken, J&J $1.2B-plus deal adds oomph to space

Jan. 2, 2025
By Randy Osborne
Kaken Pharmaceutical Co. Ltd.’s license agreement with Johnson & Johnson (J&J) for signal transducer and activator of transcription (STAT)6 inhibitor KP-723 could presage further deals in STAT6, where a number of developers are active. Kaken’s arrangement with J&J involves the global development, manufacturing and sale of KP-723, which has reached the preclinical stage. Tokyo-based Kaken will take the drug through phase I trials, after which J&J takes over.
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Obesity, fat cell research concept image
Endocrine/metabolic

Hoth acquires license to technology developed by the VA and Emory University

Dec. 30, 2024
Hoth Therapeutics Inc. has entered into an exclusive patent license agreement with the U.S. Department of Veterans Affairs (VA), providing Hoth with exclusive rights to a jointly owned patent portfolio co-developed by the VA and Emory University.
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Bioarctic, Bristol Myers join efforts in $1.35B Alzheimer’s deal

Dec. 23, 2024
By Karen Carey
In a deal worth $100 million up front and up to $1.25 billion in milestone payments, Bioarctic AB licensed its pyroglutamate-amyloid-β (pyroglutamate-Aβ) antibody program to Bristol Myers Squibb Co. to advance treatments for Alzheimer’s disease.
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