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BioWorld - Monday, February 16, 2026
Home » Topics » Deals and M&A

Deals and M&A
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Digital heart illustration

Braveheart licenses Hengrui's heart drug HRS-1893 in $1B deal

Sep. 5, 2025
By Marian (YoonJee) Chu
No Comments
Braveheart Bio Inc. is paying $65 million up front to license Jiangsu Hengrui Pharmaceuticals Co. Ltd.’s oral hypertrophic cardiomyopathy drug candidate called HRS-1893.
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Acquisition puzzle

Opzira launches with former Lumithera diagnostics

Sep. 4, 2025
By Annette Boyle
You can’t fault Alcon AG’s focus. In the midst of an extended series of acquisitions, the company has a clear vision of creating a deep ophthalmic treatment pipeline – and diagnostics fall outside that line of sight.
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Deal handshake with graphic overlay

Radiance in $1B+ pact for Novatim’s c-MET/EGFR bispecific nano ADC

Sep. 4, 2025
By Karen Carey
No Comments
About two years since its founding, new company Radiance Biopharma Inc. signed a deal in which it could pay up to $1.165 billion to Novatim Immune Therapeutics Co. Ltd. for global rights outside of certain Asian countries to a bispecific nanobody antibody-drug conjugate that targets c-MET and EGFR to treat solid tumors.
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Deal illustration

Novartis taps Argo again, inks potential $5.2B collaboration

Sep. 3, 2025
By Jennifer Boggs
No Comments
Argo Biopharmaceutical Co. Ltd. and its RNAi work drew Novartis AG back to the table for a third time, as the companies entered a potential $5.2 billion deal involving cardiovascular-focused assets, including a right to first negotiation for BW-00112, an angiopoietin-like protein 3-targeting siRNA in phase II testing in severe hypertriglyceridemia.
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Concept of business partnership
Hematologic

Enlaza takes the helm in a $2B+ Vertex deal

Sep. 3, 2025
By Lee Landenberger
No Comments
Enlaza Therapeutics Inc. will take charge of research through nominating candidates in its potentially $2 billion-plus deal with Vertex Pharmaceuticals Inc. For its efforts, Enlaza is getting $45 million in an up-front payment and equity investment, plus the opportunity to bring in more than $2 billion in research, development, regulatory and commercial milestones and tiered royalties on net sales.
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Drug design, drug delivery & technologies

Vyriad licenses Weizmann in vivo gene delivery technology

Sep. 3, 2025
No Comments
Vyriad Inc. and Yeda Research and Development Co. Ltd., the commercial arm of the Weizmann Institute of Science, have signed an exclusive license agreement for a novel viral vector targeting approach.
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Parkinson's disease illustration showing neurons containing alpha-synuclein
Neurology/psychiatric

Arrowhead and Novartis sign agreement for ARO-SNCA

Sep. 3, 2025
No Comments
Arrowhead Pharmaceuticals Inc. has announced a global licensing and collaboration agreement with Novartis AG for ARO-SNCA, Arrowhead’s preclinical stage siRNA therapy for the treatment of synucleinopathies such as Parkinson’s disease, and for additional targets.
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Concept of business partnership

Enlaza takes the helm in a $2B+ Vertex deal

Sep. 2, 2025
By Lee Landenberger
No Comments
Enlaza Therapeutics Inc. will take charge of research through nominating candidates in its potentially $2 billion-plus deal with Vertex Pharmaceuticals Inc. For its efforts, Enlaza is getting $45 million in an up-front payment and equity investment, plus the opportunity to bring in more than $2 billion in research, development, regulatory and commercial milestones and tiered royalties on net sales.
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K-Sure Chairman and President Jang Young-jin Ryu (right) with KPTA Chairman Ryu Hyung-seon at the MOU signing

Korea pharma group to support exports, Korea-Japan-China trade

Sep. 2, 2025
By Marian (YoonJee) Chu
No Comments
The Korea Pharmaceutical Traders Association said Aug. 26 that it signed a strategic agreement with Korea Trade Insurance Corp. to support South Korean companies exporting biopharmaceutical materials overseas.
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Triglycerides in blood vessel

Ionis reports sHTG win while Arrowhead inks Novartis deal

Sep. 2, 2025
By Randy Osborne
No Comments
Acute pancreatitis took center stage as Wall Street took heed of phase III data from Ionis Pharmaceuticals Inc. with olezarsen for severe hypertriglyceridemia (sHTG), while another player in the space, Arrowhead Pharmaceuticals Inc., signed a sizeable deal in a separate therapeutic area with Novartis AG.
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